Suzuki Hiromichi, Kanno Yoshihiko, Tsukamoto Isao, Tsuchiya Youhei, Sugahara Soichi
Contrib Nephrol. 2010;166:31-39. doi: 10.1159/000314850. Epub 2010 May 7.
Acute kidney injury (AKI) requiring dialysis occurs frequently, and its pathogenesis involves multiple pathways within which hemodynamic, inflammatory and nephrotoxic factors overlap. Several studies have tried to assess the risk factors leading to AKI, and found, among other factors, that preoperative renal dysfunction is important. Currently, it is uncertain when dialysis therapy should start. However, AKI after cardiac surgery should be treated early by continuous hemodialysis.
需要透析的急性肾损伤（AKI）经常发生，其发病机制涉及多个途径，其中血流动力学、炎症和肾毒性因素相互重叠。多项研究试图评估导致AKI的危险因素，发现除其他因素外，术前肾功能不全很重要。目前，尚不确定何时应开始透析治疗。然而，心脏手术后的AKI应通过连续性血液透析尽早治疗。
