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[变应性支气管肺曲霉病]

[Allergic bronchopulmonary aspergillosis].

作者信息

Hodgson Ulla

机构信息

HYKS:n keuhkosairauksien klinikka, PL 340, 00029 HUS.

出版信息

Duodecim. 2010;126(4):356-63.

Abstract

The number of patients with allergic bronchopulmonary aspergillosis is estimated to be between 2500 and 5000 in Finland. Genetic factors and bronchial epithelial cells in those having asthma or cystic fibrosis may upon exposure to Aspergillus fungus lead to airway inflammation that can slowly damage the lung tissue. Treatment of the disease is primarily based on settling of the inflammation with an oral corticosteroid and currently often also with itraconazole medication directed to the inflammation and attempting to eradicate aspergillus. Long-term prognosis is quite good, provided that the disease is detected and treated at an early stage.

摘要

据估计,芬兰过敏性支气管肺曲霉病患者数量在2500至5000人之间。哮喘或囊性纤维化患者的遗传因素和支气管上皮细胞在接触曲霉菌后可能导致气道炎症,进而缓慢损害肺组织。该疾病的治疗主要基于使用口服皮质类固醇消除炎症,目前通常还会使用针对炎症并试图根除曲霉菌的伊曲康唑药物。如果该疾病在早期被发现并得到治疗,长期预后相当良好。

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