Department of Neurological Surgery, CH8N, Oregon Health and Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA.
Hematol Oncol Clin North Am. 2010 Jun;24(3):537-51. doi: 10.1016/j.hoc.2010.03.011.
Malignant epidural spinal cord compression (MESCC) is a common neurologic complication of cancer. MESCC is a medical emergency that needs rapid diagnosis and treatment to prevent undergo emergent evaluation including magnetic resonance imaging of the entire spine. If MESCC is diagnosed, corticosteroids should be administered. Simultaneously, spine surgery and oncology teams should be immediately consulted. If indicated, patients should undergo maximal tumor resection and stabilization, followed by postoperative radiotherapy. Emerging treatment options such as stereotactic radiosurgery and vertebroplasty may be able to provide some symptomatic relief for patients who are not surgical candidates.
恶性硬膜外脊髓压迫症（MESCC）是癌症的一种常见神经系统并发症。MESCC 是一种需要快速诊断和治疗的医疗紧急情况，以防止进行紧急评估，包括整个脊柱的磁共振成像。如果诊断为 MESCC，应给予皮质类固醇。同时，应立即咨询脊柱外科和肿瘤学团队。如果有指征，患者应接受最大程度的肿瘤切除和稳定，然后进行术后放疗。对于不适合手术的患者，新兴的治疗选择，如立体定向放射外科和椎体成形术，可能能够提供一些症状缓解。
