Health Protection Agency Primary Care Unit, Microbiology Department, Gloucestershire Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK.
J Antimicrob Chemother. 2010 Jul;65(7):1526-33. doi: 10.1093/jac/dkq126. Epub 2010 May 20.
To determine the effect of the 2008 English public antibiotic campaigns.
English and Scottish (acting as controls) adults aged > or = 15 years were questioned face to face about their attitudes to and use of antibiotics, in January 2008 (1888) before and in January 2009 (1830) after the antibiotic campaigns.
Among English respondents, there was a small increase in recollection of campaign posters (2009 23.7% versus 2008 19.2%; P = 0.03), but this increase was only 2.3% higher in England than in Scotland. We did not detect any improvement in either England or Scotland, or any differences between England and Scotland in the understanding of the lack of benefit of antibiotics for coughs and colds, and we found no improvement in antibiotic use. We detected a significant increase in respondents retaining leftover antibiotics. Over 20% reported discussing antibiotics with their general practitioner (GP) or nurse in the year to January 2009. The offer of a delayed antibiotic prescription was reported significantly more often by English respondents (19% versus 8% Scottish in 2009; P = 0.01), and English respondents were advised to use other remedies for coughs and colds significantly more often in the year to January 2009 (12.7% in 2009 versus 7.4% in 2008; P < 0.001).
There is little evidence that the 2008 public antibiotic campaigns were effective. The use and visibility of future campaign materials needs auditing. A carefully planned approach that targets the public in GP waiting rooms and through clinicians in consultations may be a more effective way of improving prudent antibiotic use.
确定 2008 年英国公共抗生素宣传活动的效果。
2008 年 1 月（1888 年）抗生素宣传活动之前，以及 2009 年 1 月（1830 年）之后，对年龄≥15 岁的英国和苏格兰（作为对照）成年人进行面对面询问，了解他们对抗生素的态度和使用情况。
在英国的受访者中，回忆起宣传海报的人数略有增加（2009 年为 23.7%，2008 年为 19.2%；P=0.03），但这一增幅在英格兰仅比苏格兰高 2.3%。我们没有发现英格兰或苏格兰有任何改善，也没有发现英格兰和苏格兰在理解抗生素对咳嗽和感冒无益方面有任何差异，而且抗生素的使用也没有改善。我们发现保留剩余抗生素的受访者数量显著增加。超过 20%的受访者报告在 2009 年 1 月之前的一年中与他们的全科医生（GP）或护士讨论过抗生素。英国受访者报告的延迟开抗生素处方的情况明显更多（2009 年为 19%，苏格兰为 8%；P=0.01），并且在 2009 年 1 月之前的一年中，英国受访者被建议更多地使用其他治疗咳嗽和感冒的方法（2009 年为 12.7%，2008 年为 7.4%；P<0.001）。
几乎没有证据表明 2008 年的公共抗生素宣传活动是有效的。未来宣传材料的使用和可见性需要进行审核。一种在全科医生候诊室和临床医生咨询中针对公众的精心策划的方法，可能是改善谨慎使用抗生素的更有效途径。
