Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Boston, MA 02114, USA.
AJR Am J Roentgenol. 2010 Jun;194(6):1635-8. doi: 10.2214/AJR.09.3561.
The purpose of this study was to evaluate the efficacy of imaging-guided percutaneous radiofrequency ablation to treat metastatic retroperitoneal disease in patients with gynecologic malignancies.
Patients with retroperitoneal metastatic disease due to gynecologic malignancies were evaluated for imaging-guided percutaneous radiofrequency ablation in this study. Efficacy of treatment was assessed by post-radiofrequency ablation activity on PET/CT scans.
Eight patients were considered for imaging-guided percutaneous radiofrequency ablation of retroperitoneal metastatic disease. Radiofrequency ablation was successfully completed in five patients with six metastatic tumors. All procedures were performed with the use of hydrodissection as an adjunct maneuver to displace adjacent structures. All patients showed absence of FDG activity on post-radiofrequency ablation PET/CT scans. Three (60%) of the five patients showed absence of FDG activity of the treated disease at 23.5 months after radiofrequency ablation.
Imaging-guided percutaneous radiofrequency ablation may be considered as an alternative to currently available therapies to treat recurrent metastatic disease due to endometrial carcinoma.
本研究旨在评估影像引导经皮射频消融治疗妇科恶性肿瘤患者腹膜后转移性疾病的疗效。
本研究对患有腹膜后转移性妇科恶性肿瘤的患者进行了影像引导经皮射频消融治疗评估。通过 PET/CT 扫描评估射频消融后的活性来评估治疗效果。
8 名患者被认为适合接受影像引导经皮射频消融治疗腹膜后转移性疾病。在 5 名患者的 6 个转移性肿瘤中成功完成了射频消融。所有操作均采用水分离作为辅助操作来移位相邻结构。所有患者在射频消融后 PET/CT 扫描上均未见 FDG 活性。在射频消融后 23.5 个月，5 名患者中有 3 名（60%）患者的治疗疾病未见 FDG 活性。
影像引导经皮射频消融术可作为治疗子宫内膜癌复发转移性疾病的替代方法。
