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在澳大利亚中部的原住民中糖尿病视网膜病变的流行情况及其相关性:澳大利亚中部眼部健康研究。

Prevalence and associations of diabetic retinopathy in indigenous Australians within central Australia: the Central Australian Ocular Health Study.

机构信息

Department of Ophthalmology, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia.

出版信息

Clin Exp Ophthalmol. 2010 May;38(4):393-7. doi: 10.1111/j.1442-9071.2010.02256.x. Epub 2010 Feb 26.

Abstract

PURPOSE

To determine the prevalence and associations of diabetic retinopathy (DR) within the indigenous Australian population living in central Australia.

METHODS

1884 individuals aged 20 years or older, living in one of 30 remote communities within the statistical local area of 'central Australia' were recruited for this study. This equated to 36% of those aged 20 years or older and 67% of those aged 40 years or older within this district. Participants were recruited as they presented to the eye clinic at each remote community. Following dilated slit-lamp fundoscopy, the amount of DR in participants with diabetes mellitus (DM) was quantified using the Early Treatment of Diabetic Retinopathy Study criteria. The presence of any DR and vision-threatening DR (clinically significant macular oedema and/or proliferative DR) in one or both eyes was presented.

RESULTS

Of those with diabetes, 22.2% (25.4% of those aged 40 years or older) had any DR and 7.0% (8.4% of those aged 40 years or older) had vision-threatening DR. Both the presence of any DR and vision-threatening DR were associated with advancing age and HbA1c level, but neither subcategory was associated with sex or self-reported hypertension.

CONCLUSION

Our study has shown similar prevalence rates for DR in indigenous Australians compared with non-indigenous Australians. However, as DM is far more prevalent among indigenous Australians, the proportion of those affected by DR across the population should be considerably higher when compared with non-indigenous Australians.

摘要

目的

确定澳大利亚中部地区土着澳大利亚人群中糖尿病视网膜病变(DR)的患病率及其相关因素。

方法

本研究招募了居住在澳大利亚中部“统计区”内 30 个偏远社区的 1884 名 20 岁或以上的个体,这相当于该地区 20 岁或以上人群的 36%和 40 岁或以上人群的 67%。参与者是在每个偏远社区的眼科诊所就诊时招募的。在进行散瞳检眼镜检查后,使用糖尿病视网膜病变早期治疗研究标准对患有糖尿病的参与者的 DR 量进行定量。报告了一只或两只眼睛中存在任何 DR 和视力威胁性 DR(临床显著黄斑水肿和/或增生性 DR)的情况。

结果

在患有糖尿病的人群中,22.2%(40 岁或以上人群的 25.4%)存在任何 DR,7.0%(40 岁或以上人群的 8.4%)存在视力威胁性 DR。任何 DR 和视力威胁性 DR 的存在均与年龄和 HbA1c 水平的增加相关,但这两个亚组均与性别或自我报告的高血压无关。

结论

我们的研究表明,与非土着澳大利亚人相比,土着澳大利亚人中 DR 的患病率相似。然而,由于 DM 在土着澳大利亚人中更为普遍,因此与非土着澳大利亚人相比,DR 患者在整个人群中的比例应该高得多。

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