Abeysena Chrishantha, Jayawardana Pushpa, Seneviratne Rohini de A
Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
J Obstet Gynaecol Res. 2010 Apr;36(2):296-303. doi: 10.1111/j.1447-0756.2009.01155.x.
To determine the effect of physical activity and psychosocial stress on low birthweight (LBW).
A prospective study was carried out in a district of Sri Lanka between May 2001 and April 2002. A total of 885 pregnant mothers were recruited at < or = 16 weeks of gestation and followed up until partus. Trimester-specific exposure statuses along with potential confounding factors were gathered on average at the 12th, 28th, and 36th weeks of gestation. Physical activities were assessed by inquiring about the duration of specific postures adopted per day by housewives during each trimester at home and both at home and during working hours for those who were engaged in paid employment. Psychosocial stress was assessed using the Modified Life Events Inventory and the General Health Questionnaire 30. LBW was defined as a birthweight of less than 2500 g. Multiple logistic regression analysis was applied for controlling confounders and the results were expressed as adjusted odds ratios (OR) and 95% confidence intervals (95%CI).
Standing > 2.5 h/day (OR 2.26; 95%CI 1.10, 4.69) during the second trimester and sleeping 8 h or less/day (OR 2.84; 95%CI 1.49, 5.40) either during the second, third or both trimesters together, an increase in maternal age in years (OR 0.92; 95%CI 0.87, 0.98), and body mass index < 19.8 kg/m(2) (OR 2.2; 95%CI 1.17, 4.22) had a statistically significant association with LBW. Psychosocial stress was not associated with LBW.
Standing > 2.5 h/day and sleeping < or = 8 h/day were risk factors for LBW, whereas psychosocial stress was not.
确定体力活动和心理社会压力对低出生体重(LBW)的影响。
2001年5月至2002年4月在斯里兰卡的一个地区进行了一项前瞻性研究。共招募了885名怀孕母亲,她们在妊娠≤16周时入组,并随访至分娩。在妊娠第12、28和36周时平均收集各孕期的暴露状况以及潜在混杂因素。通过询问家庭主妇在各孕期每天在家采取特定姿势的时长,以及询问从事有偿工作者在家和工作时的时长来评估体力活动。使用改良生活事件量表和一般健康问卷30来评估心理社会压力。低出生体重定义为出生体重小于2500克。应用多因素逻辑回归分析控制混杂因素,结果以调整后的比值比(OR)和95%置信区间(95%CI)表示。
妊娠中期每天站立>2.5小时(OR 2.26;95%CI 1.10,4.69)、在妊娠中期、晚期或两者期间每天睡眠8小时或更少(OR 2.84;95%CI 1.49,5.40)、母亲年龄增加(OR 0.92;95%CI 0.87,0.98)以及体重指数<19.8 kg/m²(OR 2.2;95%CI 1.17,4.22)与低出生体重有统计学显著关联。心理社会压力与低出生体重无关。
每天站立>2.5小时和每天睡眠≤8小时是低出生体重的危险因素,而心理社会压力不是。