Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Spine J. 2010 Jun;10(6):544-53. doi: 10.1016/j.spinee.2010.03.025.
Low back pain (LBP) is a prevalent and expensive musculoskeletal condition that predominantly occurs in working-age individuals of industrialized nations. Although numerous occupational physical activities have been implicated in its etiology, determining the causation of occupational LBP still remains a challenge.
To conduct a systematic review evaluating the causal relationship between occupational pushing or pulling and LBP.
Systematic review of the literature.
Studies reporting an association between occupational pushing or pulling and LBP.
Numerical association between exposure to pushing or pulling and the presence of LBP.
A systematic review was performed to identify, evaluate, and summarize the literature related to establishing a causal relationship, according to Bradford-Hill criteria for causation for occupational pushing or pulling and LBP. A search was conducted using Medline, EMBASE, CINAHL, Cochrane Library, and OSH-ROM, gray literature, hand-searching occupational health journals, reference lists of included studies, and expert knowledge. Methodological quality was assessed using a modified Newcastle-Ottawa Scale.
This search yielded 2,766 citations. Thirteen studies met the inclusion criteria. Eight were high-quality studies and five were low-quality studies. There was conflicting evidence with one high-quality study demonstrating a positive association between occupational pushing or pulling and LBP and five studies showing no relationship. One study reported a nonstatistically significant dose-response trend, four studies discussed temporality of which one indicated a positive finding, two studies discussed the biological plausibility of a causal link between occupational pushing or pulling and LBP, and no evidence was uncovered to assess the experiment criterion.
A qualitative summary of existing studies was not able to find any high-quality studies that fully satisfied any of the Bradford-Hill causation criteria for occupational pushing or pulling and LBP. Based on the evidence reviewed, it is unlikely that occupational pushing or pulling is independently causative of LBP in the populations of workers studied.
下背痛(LBP)是一种普遍且昂贵的肌肉骨骼疾病,主要发生在工业化国家的劳动年龄段人群中。尽管有许多职业体力活动与该病的病因有关,但确定职业性 LBP 的病因仍然具有挑战性。
系统评价评估职业性推或拉与 LBP 之间的因果关系。
文献系统评价。
报告职业性推或拉与 LBP 之间存在关联的研究。
暴露于推或拉与 LBP 存在之间的数值关联。
根据职业性推或拉与 LBP 因果关系的布拉德福-希尔标准,进行系统评价以识别、评估和总结与建立因果关系相关的文献。使用 Medline、EMBASE、CINAHL、Cochrane 图书馆和 OSH-ROM、灰色文献、职业健康期刊的手工检索、纳入研究的参考文献以及专家知识进行检索。使用改良的纽卡斯尔-渥太华量表评估方法学质量。
本次检索产生了 2766 条引文。13 项研究符合纳入标准。其中 8 项为高质量研究,5 项为低质量研究。证据相互矛盾,一项高质量研究表明职业性推或拉与 LBP 之间存在正相关,五项研究则未显示出相关性。一项研究报告了非统计学显著的剂量反应趋势,四项研究讨论了时间关系,其中一项表明存在阳性发现,两项研究讨论了职业性推或拉与 LBP 之间因果关系的生物学合理性,但没有发现证据可以评估实验标准。
对现有研究的定性总结未能找到任何高质量的研究,这些研究完全满足职业性推或拉与 LBP 因果关系的任何布拉德福-希尔标准。根据审查的证据,职业性推或拉不太可能独立导致研究人群中的 LBP。