帕金森病谜题中的缺失环节。
Missing pieces in the Parkinson's disease puzzle.
机构信息
Department of Neurology, Clínica Universitaria and Medical School of Navarra, Neuroscience Centre, Center for Applied Medical Research, Pamplona, Spain.
出版信息
Nat Med. 2010 Jun;16(6):653-61. doi: 10.1038/nm.2165. Epub 2010 May 23.
DOI:10.1038/nm.2165
PMID:20495568
Abstract
Parkinson's disease is a neurodegenerative process characterized by numerous motor and nonmotor clinical manifestations for which effective, mechanism-based treatments remain elusive. Here we discuss a series of critical issues that we think researchers need to address to stand a better chance of solving the different challenges posed by this pathology.
摘要
帕金森病是一种神经退行性疾病，其特征是存在多种运动和非运动临床表现，但目前仍缺乏有效的、基于机制的治疗方法。在这里，我们讨论了一系列我们认为研究人员需要解决的关键问题，以期更好地解决该病理学带来的不同挑战。
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