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一项针对心力衰竭的心脏康复计划能否减少高危患者的住院次数并改善其预后?

Can a heart failure-specific cardiac rehabilitation program decrease hospitalizations and improve outcomes in high-risk patients?

作者信息

Davidson Patricia M, Cockburn Jill, Newton Phillip J, Webster Julie K, Betihavas Vasiliki, Howes Laurie, Owensby Dwain O

机构信息

Curtin University of Technology, 39 Regent Street, Chippendale, NSW 2008, Australia.

出版信息

Eur J Cardiovasc Prev Rehabil. 2010 Aug;17(4):393-402. doi: 10.1097/HJR.0b013e328334ea56.

Abstract

BACKGROUND

Heart failure is a common and costly condition, particularly in the elderly. A range of models of interventions have shown the capacity to decrease hospitalizations and improve health-related outcomes. Potentially, cardiac rehabilitation models can also improve outcomes.

AIM

To assess the impact of a nurse-coordinated multidisciplinary, cardiac rehabilitation program to decrease hospitalizations, increase functional capacity, and meet the needs of patients with heart failure.

METHOD

In a randomized control trial, a total of 105 patients were recruited to the study. Patients in the intervention group received an individualized, multidisciplinary 12-week cardiac rehabilitation program, including an individualized exercise component tailored to functional ability and social circumstances. The control group received an information session provided by the cardiac rehabilitation coordinator and then follow-up care by either their cardiologist or general practitioner. This trial was stopped prematurely after the release of state-based guidelines and funding for heart failure programs.

RESULTS

During the study period, patients in the intervention group were less likely to have been admitted to hospital for any cause (44 vs. 69%, P = 0.01) or after a major acute coronary event (24 vs. 55%, P = 0.001). Participants in the intervention group were more likely to be alive at 12 months, (93 vs. 79%; P = 0.03) (odds ratio = 3.85; 95% confidence interval=1.03-14.42; P = 0.0042). Quality of life scores improved at 3 months compared with baseline (intervention t = o/-4.37, P<0.0001; control t = /-3.52, P<0.01). Improvement was also seen in 6-min walk times at 3 months compared with baseline in the intervention group (t = 3.40; P = 0.01).

CONCLUSION

This study shows that a multidisciplinary heart failure cardiac rehabilitation program, including an individualized exercise component, coordinated by a specialist heart failure nurse can substantially reduce both all-cause and cardiovascular readmission rates, improve functional status at 3 months and exercise tolerance.

摘要

背景

心力衰竭是一种常见且代价高昂的疾病,在老年人中尤为如此。一系列干预模式已显示出降低住院率和改善健康相关结局的能力。心脏康复模式也有可能改善结局。

目的

评估由护士协调的多学科心脏康复项目对降低住院率、提高功能能力以及满足心力衰竭患者需求的影响。

方法

在一项随机对照试验中,共招募了105名患者参与研究。干预组患者接受了为期12周的个性化多学科心脏康复项目,包括根据功能能力和社会情况量身定制的个性化运动部分。对照组接受了由心脏康复协调员提供的信息介绍会,然后由他们的心脏病专家或全科医生进行后续护理。在基于州的心力衰竭项目指南和资金发布后,该试验提前终止。

结果

在研究期间,干预组患者因任何原因住院的可能性较小(44%对69%,P = 0.01),或在发生重大急性冠状动脉事件后住院的可能性较小(24%对55%,P = 0.001)。干预组参与者在12个月时存活的可能性更大(93%对79%;P = 0.03)(优势比 = 3.85;95%置信区间 = 1.03 - 14.42;P = 0.0042)。与基线相比,干预组在3个月时生活质量评分有所改善(干预组t = -4.37,P < 0.0001;对照组t = -3.52,P < 0.01)。与基线相比,干预组在3个月时6分钟步行时间也有所改善(t = 3.40;P = 0.01)。

结论

本研究表明,由专业心力衰竭护士协调的多学科心力衰竭心脏康复项目,包括个性化运动部分,可大幅降低全因和心血管再入院率,改善3个月时的功能状态和运动耐量。

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