Effect of diltiazem, nifedipine and verapamil on the antinociceptive action of acetylsalicylic acid in mice.
作者信息
al-Humayyd M S
机构信息
Department of Medical Pharmacology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
出版信息
Gen Pharmacol. 1991;22(1):121-5. doi: 10.1016/0306-3623(91)90321-v.
PMID:2050280
Abstract
- Diltiazem, verapamil and nifedipine produced a dose-dependent analgesic response in mice. 2. A fixed oral dose of acetylsalicylic acid increased this analgesic response. 3. Analgesia was maintained when mice were treated chronically with calcium channel blockers alone or when combined with aspirin.
摘要
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