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膝关节剥脱性骨软骨炎的自体骨软骨移植。前瞻性病例系列的初步结果。

Osteochondral autograft transplantation for osteochondritis dissecans of the knee. Preliminary results of a prospective case series.

作者信息

Smolders José M H, Kock Niels B, Koëter Sander, Van Susante Job L C

机构信息

Department of Orthopaedic Surgery, Rijnstate Hospital, Arnhem, The Netherlands.

出版信息

Acta Orthop Belg. 2010 Apr;76(2):208-18.

Abstract

To evaluate the short-term outcome of osteochondritis dissecans (OCD) treated with mosaic osteochondral autograft transplantation (OAT), 7 male patients (mean age 33.4) with 8 OCD lesions on the lateral border of the medial femoral condyle were prospectively followed. Patients were evaluated by the International Knee Documention Committee (IKDC) score and the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaires preoperatively, at 6 months and 1 year after surgery. MRI evaluation using the modified Sanders score was performed at 1-year follow-up. The IKDC subjective score and all subscales of the KOOS improved significantly. MRI evaluation showed good surface congruency, no oedema or protuberance of the osteocartilaginous cylinders, good similarity of cartilage thickness and a non-complete osseous integration. With the small numbers of patients available, no correlation could be found between MRI findings, percentage of defect coverage and patient satisfaction. Mosaic OAT appeared in this study as a valid treatment option in selected cartilage defects. OCD lesions improved significantly following osteochondral transplantation. The limitations of this technique are the number and size of the plugs needed to repair the defect. Future research should focus on identifying the appropriate choice of operative treatment for well defined subtypes of articular cartilage lesions, rather than searching for one superior technique for all.

摘要

为评估镶嵌式自体骨软骨移植术(OAT)治疗剥脱性骨软骨炎(OCD)的短期疗效,对7例男性患者(平均年龄33.4岁)进行了前瞻性随访,这些患者在内侧股骨髁外侧缘有8处OCD损伤。术前、术后6个月和1年,采用国际膝关节文献委员会(IKDC)评分和膝关节损伤与骨关节炎疗效评分(KOOS)问卷对患者进行评估。在1年随访时,采用改良桑德斯评分进行MRI评估。IKDC主观评分和KOOS的所有子量表均有显著改善。MRI评估显示表面一致性良好,骨软骨柱无水肿或隆起,软骨厚度相似性良好,骨整合不完全。由于可用患者数量较少,MRI表现、缺损覆盖百分比与患者满意度之间未发现相关性。在本研究中,镶嵌式OAT似乎是治疗特定软骨缺损的有效选择。骨软骨移植术后OCD损伤有显著改善。该技术的局限性在于修复缺损所需移植物的数量和大小。未来的研究应集中于为明确的关节软骨损伤亚型确定合适的手术治疗选择,而不是寻找一种适用于所有情况的 superior 技术。 (注:原文中“superior”未翻译准确,可根据上下文进一步优化表述,比如“更优的”等 )

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