Nancoz Olivier, Kherad Omar, Perrin Etienne, Hsu Christophe, Lobrinus Johannes Alexander, Nendaz Mathieu
Department of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland.
J Med Case Rep. 2010 May 26;4:155. doi: 10.1186/1752-1947-4-155.
Because a substantial number of patients present with few or atypical symptoms, the recognition of tuberculosis remains challenging. Disseminated tuberculosis presenting with septic shock has already been described in some case reports, but, to the best of our knowledge, it has never been associated with polymorphonuclear effusion.
We describe the case of a 27-year-old man from western Africa who was seropositive for human immunodeficiency virus. He presented with pleural and abdominal polymorphonuclear effusions and quickly developed septic shock due to disseminated Mycobacterium tuberculosis infection leading to multiple organ failure and death.
In high-risk patients, Mycobacterium tuberculosis infection should be considered even in exceptional clinical presentations, such as septic shock and polymorphonuclear effusions.
由于大量患者症状较少或不典型,结核病的诊断仍然具有挑战性。一些病例报告中已经描述了播散性结核病伴发感染性休克的情况,但据我们所知,它从未与多形核细胞渗出相关。
我们描述了一名来自西非的27岁男性病例,他的人类免疫缺陷病毒血清学检测呈阳性。他出现了胸膜和腹腔多形核细胞渗出,并因播散性结核分枝杆菌感染迅速发展为感染性休克,导致多器官功能衰竭和死亡。
在高危患者中,即使临床表现特殊,如感染性休克和多形核细胞渗出,也应考虑结核分枝杆菌感染。