Department of Pediatric Cardiology, Lund University and Lund University Hospital, Lund, Sweden.
Catheter Cardiovasc Interv. 2010 Dec 1;76(7):1027-32. doi: 10.1002/ccd.22605.
To report the late coronary complications and their treatment after arterial switch operation (ASO).
Asymptomatic patients after ASO may have coronary ostial stenosis or obstruction.
Since 1980, 279 patients were operated with ASO. At the time of preparing this article, selective follow-up coronary angiograms were done on 81 patients.
Coronary stenosis was found in six patients. A 6-year-old patient with left coronary artery (LCA) ostial stenosis and a 9-year-old patient with conus branch occlusion had good collaterals without a need for further treatment. One patient with LCA obstruction, myocardial infarction, and left ventricular failure was operated with osteoplasty at age of 16 years. In three essentially asymptomatic patients, stenting of LCA ostium stenosis was done: in two of them with drug-eluting stents at 9 and 10 years of age and in one with bare-metal stent at 18 years of age. One of these patients was earlier treated with balloon dilatation at 5 years of age which caused intimal dissection.
Asymptomatic patients with an uneventful course after ASO may have coronary obstruction. This necessitates follow-up coronary evaluation in all patients. Stenting of the coronary arteries is an option for treatment.
报告动脉调转术(ASO)后晚期冠状动脉并发症及其治疗方法。
ASO 后无症状患者可能存在冠状动脉口狭窄或阻塞。
自 1980 年以来,共有 279 例患者接受 ASO 手术。在撰写本文时,对 81 例患者进行了选择性随访冠状动脉造影。
6 例患者发现冠状动脉狭窄。1 例 6 岁患者存在左冠状动脉(LCA)口狭窄,1 例 9 岁患者存在圆锥支闭塞,两者均有良好的侧支循环,无需进一步治疗。1 例 LCA 阻塞、心肌梗死和左心室衰竭患者在 16 岁时接受了骨成形术。3 例基本无症状患者行 LCA 口狭窄支架置入术:其中 2 例在 9 岁和 10 岁时行药物洗脱支架置入术,1 例在 18 岁时行裸金属支架置入术。其中 1 例在 5 岁时曾接受球囊扩张治疗,导致内膜夹层。
ASO 后无并发症且无症状的患者可能存在冠状动脉阻塞。因此,所有患者均需进行随访冠状动脉评估。冠状动脉支架置入术是一种治疗选择。