Smith Stella Ruth, Aljarabah Moayad, Ferguson Graeme, Babar Zahir
Department of Surgery and Anaesthesia, Royal Bolton NHS Foundation Trust, Minerva Road, Farnworth, Bolton, Lancashire BL4 0JR, UK.
J Med Case Rep. 2010 May 27;4:161. doi: 10.1186/1752-1947-4-161.
Necrotizing fasciitis is a rare condition with a mortality rate of around 34%. It can be mono- or polymicrobial in origin. Monomicrobial infections are usually due to group A streptococcus and their incidence is on the rise. They normally occur in healthy individuals with a history of trauma, surgery or intravenous drug use. Post-operative necrotizing fasciitis is rare but accounts for 9 to 28% of all necrotizing fasciitis. The incidence of wound infection following saphenofemoral junction ligation and vein stripping is said to be less than 3%, although this complication is probably under-reported. We describe a case of group A streptococcus necrotizing fasciitis following saphenofemoral junction ligation and vein stripping.
A 39-year-old woman presented three days following a left sided saphenofemoral junction ligation with long saphenous vein stripping at another institution. She had a three day history of fever, rigors and swelling of the left leg. She was pyrexial and shocked. She had a very tender, swollen left groin and thigh, with a small blister anteriorly and was in acute renal failure. She was prescribed intravenous penicillin and diagnosed with necrotizing fasciitis. She underwent extensive debridement of her left thigh and was commenced on clindamycin and imipenem. Post-operatively, she required ventilatory and inotropic support with continuous veno-venous haemofiltration. An examination 12 hours after surgery showed no requirement for further debridement. A group A streptococcus, sensitive to penicillin, was isolated from the debrided tissue. A vacuum assisted closure device was fitted to the clean thigh wound on day four and split-skin-grafting was performed on day eight. On day 13, a wound inspection revealed that more than 90% of the graft had taken. Antibiotics were stopped on day 20 and she was discharged on day 22.
Necrotizing fasciitis is a very serious complication for a relatively minor, elective procedure. To the best of our knowledge, this is the first report in the English-language literature of this complication arising from a standard saphenofemoral junction ligation and vein stripping. It highlights the need to be circumspect when offering patients surgery for non-life-threatening conditions.
坏死性筋膜炎是一种罕见疾病,死亡率约为34%。其病因可为单一微生物或多种微生物感染。单一微生物感染通常由A组链球菌引起,且发病率呈上升趋势。此类感染通常发生在有创伤、手术或静脉吸毒史的健康个体中。术后坏死性筋膜炎虽罕见,但占所有坏死性筋膜炎病例的9%至28%。隐股静脉结扎和大隐静脉剥脱术后伤口感染的发生率据报道低于3%,不过这种并发症可能存在报告不足的情况。我们报告一例隐股静脉结扎和大隐静脉剥脱术后发生A组链球菌坏死性筋膜炎的病例。
一名39岁女性在另一机构接受左侧隐股静脉结扎及大隐静脉剥脱术后三天就诊。她有三天的发热、寒战及左腿肿胀病史。她发热且休克。左侧腹股沟和大腿压痛明显、肿胀,前部有一个小水泡,且出现急性肾衰竭。她接受了静脉注射青霉素治疗,并被诊断为坏死性筋膜炎。她接受了左侧大腿广泛清创术,并开始使用克林霉素和亚胺培南。术后,她需要通气及血管活性药物支持,并进行持续静脉 - 静脉血液滤过。术后12小时检查显示无需进一步清创。从清创组织中分离出对青霉素敏感的A组链球菌。术后第四天在清洁的大腿伤口上安装了负压封闭引流装置,第八天进行了植皮手术。术后第13天,伤口检查显示超过90%的移植皮肤存活。术后第20天停用抗生素,第22天出院。
对于相对较小的择期手术而言,坏死性筋膜炎是一种非常严重的并发症。据我们所知,这是英文文献中关于标准隐股静脉结扎和大隐静脉剥脱术后出现这种并发症的首例报告。这凸显了在为非危及生命的疾病为患者提供手术时需谨慎的必要性。