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多节段颈椎椎体次全切除后路动态钢板固定术后早期重建失败的危险因素。

Risk factors for early reconstruction failure of multilevel cervical corpectomy with dynamic plate fixation.

机构信息

Department of Orthopedic and Spinal Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

Spine (Phila Pa 1976). 2011 Apr 20;36(9):E582-7. doi: 10.1097/BRS.0b013e3181e0f06a.

Abstract

STUDY DESIGN

Retrospective case series.

OBJECTIVE

To investigate risk factors for early reconstruction failure of multilevel cervical corpectomy with dynamic plate fixation.

SUMMARY OF BACKGROUND DATA

For anterior cervical decompression and fusion, reinforcement by plate fixation was performed to decrease early reconstruction failure and to increase the fusion rate. However, a relatively high complication rate such as graft dislodgement, has been reported in patients undergoing multilevel corpectomy and reconstruction. Risk factors associated with early reconstruction failure have not been explicitly described.

METHODS

In 30 instrumented multilevel corpectomy and reconstruction, medical records and radiographic studies were reviewed to investigate risk factors with regard to sagittal alignment of the cervical spine, graft subsidence, screws used in fixation, endplate preparation, and intermediate screw for fibular graft.

RESULTS

Reconstruction failures included anterior slipping at the bottom of the graft in 2 cases, fracture of the C7 vertebral body in 2 cases, and pullout of a screw in 2 cases. Four patients were found to have nonunion of the graft at the final follow-up, but none had experienced early reconstruction failure.On radiologic measurement, the fusion area lordotic angle after surgery in the patients with reconstruction failures was significantly larger than that of the patients with no complications. The postoperative C2-C7 lordotic angles of the patients with reconstruction failure were also larger, but this trend was not statistically significant. No other factor, such as age and gender, type of screw used, intermediate screw or preservation of the endplates was related to reconstruction failures in this study.

CONCLUSION

Postoperative cervical hyperlordosis may adversely affect graft stability in the early postoperative period of the surgery of corpectomy and reconstruction with dynamic plate fixation.

摘要

研究设计

回顾性病例系列研究。

目的

探讨颈椎前路椎体次全切融合术(ACCF)术后早期重建失败的危险因素。

背景资料概要

颈椎前路减压融合术(ACCF)采用钢板固定进行加固,以降低早期重建失败的风险,提高融合率。然而,接受多节段椎体次全切和重建的患者报告了较高的并发症发生率,如移植物移位、螺钉松动等。目前尚未明确描述与早期重建失败相关的危险因素。

方法

对 30 例颈椎前路多节段次全切融合内固定术的病历和影像学资料进行回顾性研究,分析颈椎矢状位对线、植骨下沉、固定用螺钉、终板准备和腓骨移植中间螺钉等与早期重建失败相关的危险因素。

结果

重建失败包括 2 例植骨底部前滑、2 例 C7 椎体骨折和 2 例螺钉松动。4 例患者最终随访时发现植骨未融合,但均未发生早期重建失败。影像学测量显示,重建失败患者术后融合区前凸角明显大于无并发症患者。重建失败患者术后 C2-C7 后凸角也较大,但无统计学意义。本研究中,其他因素,如年龄、性别、螺钉类型、中间螺钉或终板的保留,与重建失败无关。

结论

术后颈椎过度前凸可能会影响颈椎前路椎体次全切融合术(ACCF)术后早期植骨的稳定性。

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