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运动员膝关节软骨缺损的治疗。

Treatment of chondral defects in the athlete's knee.

机构信息

Department of Orthopaedics, Division of Sports Medicine Cartilage Repair Center, The Ohio State University Medical Center, 2050 Kenny Road, Columbus, OH 43221, USA.

出版信息

Arthroscopy. 2010 Jun;26(6):841-52. doi: 10.1016/j.arthro.2009.12.030.

Abstract

PURPOSE

To determine which surgical technique(s) has improved outcomes and enables athletes to return to their preinjury level of sports and which patient and defect factors significantly affect outcomes after cartilage repair or restoration.

METHODS

We conducted a search of multiple medical databases, evaluating studies of articular cartilage repair in athletes.

RESULTS

We identified 11 studies for inclusion (658 subjects). Only 1 randomized clinical trial was identified. All other studies were prospective cohorts, case-control studies, or case series reporting results after either microfracture or autologous chondrocyte implantation (ACI) or osteoarticular transplantation (OATS). Eight different clinical outcomes measures were used. Better clinical outcomes were observed after ACI and OATS versus microfracture. Results after microfracture tended to deteriorate with time. The overall rate of return to preinjury level of sports was 66%. The timing of return to the preinjury level of sports was fastest after OATS and slowest after ACI. Defect size of less than 2 cm(2), preoperative duration of symptoms of less than 18 months, no prior surgical treatment, younger patient age, and higher preinjury and postsurgical level of sports all correlated with improved outcomes after cartilage repair, especially ACI. Results after microfracture were worse with larger defects. The rate of return to sports was generally lower after microfracture versus ACI or OATS, and if a patient was able to return to sports, performance was diminished as well.

CONCLUSIONS

Management of chondral defects in the athlete is complex and multifactorial. There is little high-level evidence to support one procedure over another, although good short-term and midterm outcomes with a fair rate of return to preinjury level of sports can be achieved with cartilage repair and restoration in the athlete.

LEVEL OF EVIDENCE

Level IV, systematic review.

摘要

目的

确定哪种手术技术(s)可以改善结果,并使运动员能够恢复到受伤前的运动水平,以及哪些患者和缺陷因素会显著影响软骨修复或重建后的结果。

方法

我们对多个医学数据库进行了搜索,评估了运动员关节软骨修复的研究。

结果

我们确定了 11 项纳入研究(658 例受试者)。仅发现 1 项随机临床试验。所有其他研究都是前瞻性队列研究、病例对照研究或病例系列研究,报告了微骨折或自体软骨细胞移植(ACI)或骨软骨移植(OATS)后的结果。使用了 8 种不同的临床结果测量方法。ACI 和 OATS 后的临床结果优于微骨折。微骨折后结果随时间趋于恶化。重返受伤前运动水平的总体比率为 66%。OATS 后重返受伤前运动水平的时间最快,ACI 后最慢。缺陷小于 2cm(2)、术前症状持续时间小于 18 个月、无既往手术治疗、患者年龄较小以及术前和术后运动水平较高,均与软骨修复后(尤其是 ACI)的结果改善相关。微骨折后缺陷较大,结果较差。微骨折后重返运动的比率通常低于 ACI 或 OATS,而且如果患者能够重返运动,运动表现也会下降。

结论

运动员的软骨缺陷的处理是复杂的,多因素的。虽然软骨修复和重建可以在运动员中获得良好的短期和中期结果,并能以相当高的比率恢复到受伤前的运动水平,但几乎没有高水平的证据支持一种手术优于另一种手术。

证据水平

IV 级,系统评价。

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