Anastasiadis Kyriakos, Asteriou Christos, Deliopoulos Apostolos, Argiriadou Helena, Karapanagiotidis Georgios, Antonitsis Polychronis, Grosomanidis Vasilios, Misias Georgios, Papakonstantinou Christos
Department of Cardiothoracic Surgery, AHEPA University Hospital, Thessaloniki, Greece.
Perfusion. 2010 Jul;25(4):197-203. doi: 10.1177/0267659110373840. Epub 2010 Jun 1.
During the last decade, minimized extracorporeal circulation (MECC) systems have shown beneficial effects to the patients over the conventional cardiopulmonary bypass (CECC) circuits. This is a prospective randomized study of 99 patients who underwent coronary artery bypass grafting (CABG) surgery, evaluating the postoperative haematological effects of these systems. Less haemodilution (p=0.001) and markedly less haemolysis (p<0.001), as well as better preservation of the coagulation system integrity (p=0.01), favouring the MECC group, was found. As a clinical result, less bank blood requirements were noted and a quicker recovery, as far as mechanical ventilation support and ICU stay are concerned, was evident with the use of MECC systems. As a conclusion, minimized extracorporeal circulation systems may attenuate the adverse effects of conventional circuits on the haematological profile of patients undergoing CABG surgery.
在过去十年中，体外循环（MECC）系统相较于传统心肺转流（CECC）回路已显示出对患者的有益效果。这是一项针对99例行冠状动脉旁路移植术（CABG）手术患者的前瞻性随机研究，评估了这些系统的术后血液学影响。结果发现，MECC组的血液稀释程度更低（p = 0.001）、溶血明显更少（p < 0.001），并且凝血系统完整性的保存更好（p = 0.01）。作为临床结果，使用MECC系统时，所需库存血更少，并且在机械通气支持和重症监护病房（ICU）停留时间方面恢复更快。总之，体外循环系统可减轻传统回路对接受CABG手术患者血液学特征的不利影响。
