Saïdani Mabrouka, Kammoun Skander, Boutiba-Ben Boubaker Ilhem, Ben Redjeb Saïda
Laboratoire de Microbologie, Hôpital Charles Nicolle de Tunis.
Tunis Med. 2010 May;88(5):360-2.
Although non- diphtherial corynebacteria are ubiquitous in nature and commonly colonize the skin and mucous membranes of humans, they rarely account for clinical infections.
we report a case of infection due to non- diphtherial corynebacteria, Corynebacterium propinquum.
A Tunisian male patient of 67 years old was admitted to orthopedic surgery and traumatology ward of Charles Nicolle university hospital of Tunis (Tunisia) for a left elbow trauma. He was treated by osteosynthesis and received an antibioprophylactic therapy with amoxicilline-clavulanate and gentamicin association. No postoperative incident was noted. When he was readmitted a month later for the osteosynthesis material removal, clinical examination found a pus collection in the operated elbow. Specimen analysis showed a Gram positive stained bacilli identified as C. propinquum. The organism was resistant only to penicillin G and sulfamethoxazole-trimethoprim association. The patient was treated with ofloxacin (2 g per day for 8 days) and gentamicin (160 mg per day for 5 days) with clinical improvement.
According to literature, infections due to C. propinquum are rare, occurring especially in patients with medical device or immunocompromised. Thus, this pathogen should be taken in consideration in such situations.
尽管非白喉棒状杆菌在自然界中普遍存在,且通常定殖于人类的皮肤和黏膜,但它们很少引起临床感染。
我们报告一例由非白喉棒状杆菌——亲近棒状杆菌引起的感染病例。
一名67岁的突尼斯男性患者因左肘部创伤入住突尼斯查尔斯·尼科勒大学医院的骨科手术和创伤科病房。他接受了骨固定治疗,并接受了阿莫西林 - 克拉维酸与庆大霉素联合的抗生素预防性治疗。术后未出现任何并发症。一个月后,当他因取出骨固定材料再次入院时,临床检查发现手术肘部有积脓。标本分析显示革兰氏阳性染色杆菌,鉴定为亲近棒状杆菌。该菌仅对青霉素G和磺胺甲恶唑 - 甲氧苄啶联合制剂耐药。患者接受氧氟沙星(每天2克,共8天)和庆大霉素(每天160毫克,共5天)治疗后临床症状改善。
根据文献,亲近棒状杆菌引起的感染很少见,尤其发生在使用医疗器械的患者或免疫功能低下者中。因此,在这种情况下应考虑到这种病原体。