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食盐氟化:其预防龋齿功效的荟萃分析。

Salt fluoridation: a meta-analysis of its efficacy for caries prevention.

作者信息

Yengopal V, Chikte U M E, Mickenautsch S, Oliveira L B, Bhayat A

机构信息

Community Dentistry, Division of Public Oral Health, University of the Witwatersrand Johannesburg, 7 York Rd, Parktown, Johannesburg 2193, South Africa.

出版信息

SADJ. 2010 Mar;65(2):60-4, 66-7.

Abstract

UNLABELLED

The aim of this meta-analysis was to assess the caries preventive effect of Salt fluoridation (SF) in the permanent dentition in children. THE OBJECTIVES WERE TO COMPARE: (1) the caries preventive effects of SF versus no exposure in different age cohorts (6-8; 9-12; and 13-15 years old); (2) SF versus other community based interventions (milk or water fluoridation [WF]).

METHODS

9 English and 2 non-English databases were searched for papers that reported on the caries preventive effect of groups (with controls) that were exposed to SF in the form of mean DMFT scores with standard deviations. Differences in exposed and nonexposed groups were computed on the basis of weighted mean differences (WMDs) with 95% confidence intervals (CIs).

RESULTS

For 6-8 year olds, the pooled reduction in DMFT scores was -0.98 [95% CI: -1.68 to -0.29]; for 9-12 year olds, it was -2.13 [95% CI: -2.55 to -1.70] and for the 13-15 year old groups, -4.22 [95% CI: -6.84 to -1.55]. All the analyses favoured the SF groups (p <0.001). For SF versus WF, there was no difference (-0.11 reduction [95% CI: -0.29 to +0.07]).

CONCLUSION

Within limitations, the pooled estimates of the WMDs for the different age cohorts favoured SF versus no exposure.

摘要

未标注

本荟萃分析的目的是评估儿童恒牙列中食盐氟化(SF)的防龋效果。目标是比较:(1)不同年龄组(6 - 8岁;9 - 12岁;13 - 15岁)中SF与未接触组的防龋效果;(2)SF与其他社区干预措施(牛奶或水氟化[WF])的效果。

方法

检索了9个英文和2个非英文数据库,查找以平均DMFT评分及标准差形式报告接触SF组(有对照组)防龋效果的论文。根据加权平均差(WMD)及95%置信区间(CI)计算暴露组和非暴露组的差异。

结果

对于6 - 8岁儿童,DMFT评分的合并降低值为 -0.98 [95% CI:-1.68至 -0.29];对于9 - 12岁儿童,为 -2.13 [95% CI:-2.55至 -1.70],对于13 - 15岁组,为 -4.22 [95% CI:-6.84至 -1.55]。所有分析均支持SF组(p <0.001)。对于SF与WF的比较,无差异(降低0.11 [95% CI:-0.29至 +0.07])。

结论

在一定局限性内,不同年龄组WMD的合并估计结果支持SF组与未接触组相比的防龋效果。

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