Suppr超能文献

睾酮用于治疗男性“迟发性性腺功能减退”?

Testosterone for 'late-onset hypogonadism' in men?

出版信息

Drug Ther Bull. 2010 Jun;48(6):69-72. doi: 10.1136/dtb.2010.01.0004.

Abstract

Testosterone replacement therapy is indicated in men with a deficiency or absence of endogenous testosterone due to classical primary or secondary hypogonadism.1-8 Of note, however, some testosterone preparations are also specifically licensed for "male climacteric symptoms like decreased libido".1-3 This indication is based on the concept of 'late-onset hypogonadism', a term used to describe the decline in testosterone concentrations with age plus associated symptoms (by analogy with the female menopause/climacteric).9 Other terms for 'late-onset hypogonadism' include 'partial androgen deficiency in the ageing male'. It has also been known as 'andropause' or, colloquially, 'male menopause', but these latter terms are not usually used by specialists nowadays. Here we discuss whether 'late-onset hypogonadism' is a distinct medical entity, and whether testosterone replacement has a role in older men with low testosterone concentrations but not classical hypogonadism.

摘要

由于典型的原发性或继发性性腺功能减退导致内源性睾酮缺乏或缺失的男性,适用睾酮替代疗法。1-8 然而,值得注意的是,一些睾酮制剂还专门获批用于治疗“性欲减退等男性更年期症状”。1-3 这一适应症基于“迟发性性腺功能减退”的概念,该术语用于描述随着年龄增长睾酮浓度下降以及相关症状(类比女性绝经/更年期)。9 “迟发性性腺功能减退”的其他术语包括“老年男性部分雄激素缺乏”。它也曾被称为“男性更年期”,通俗来讲就是“男性绝经”,但如今专家们通常不使用后两个术语。在此我们讨论“迟发性性腺功能减退”是否为一个独特的医学实体,以及睾酮替代疗法在睾酮浓度低但无典型性腺功能减退的老年男性中是否起作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验