Kucera M, Brabcová H
I. interní klinika KUNZ FN Plzen.
Vnitr Lek. 1991 Apr;37(4):366-8.
In 50 patients with confirmed or classical rheumatoid arthritis the serum iron level (FeS) was examined (in some repeatedly), the total number of examinations being 82. In 51.1% reduced values were recorded. In 27 subjects of the group the total iron binding capacity was assessed. In none of the patients reduced values were found, in 24 the values were at the upper borderline of normal values and in one instance the value was elevated. In 13 patients with a low FeS with a normal or elevated total iron binding capacity Ferronat Retard was administered. The FeS level reached relatively rapidly normal values which in the author's opinion is rather a manifestation of receding activity of rheumatoid arthritis. They consider administration of iron preparations even in patients with a relatively high total iron binding capacity problematical, except when there is justified suspicion of iron ion losses via the gastrointestinal tract or in malnutrition. Iron administration did not cause deterioration of the rheumatic process.
对50例确诊或典型类风湿性关节炎患者检测了血清铁水平（FeS）（部分患者多次检测），检测总数为82次。51.1%的患者记录到FeS值降低。对该组中的27名受试者评估了总铁结合力。未发现患者总铁结合力值降低，24例患者的值处于正常范围上限，1例升高。对13例FeS低但总铁结合力正常或升高的患者给予了缓释铁剂（Ferronat Retard）。FeS水平相对较快地达到正常，作者认为这相当于是类风湿性关节炎活动减退的一种表现。他们认为，即使在总铁结合力相对较高的患者中，给予铁剂治疗也存在问题，除非有合理怀疑存在经胃肠道铁离子丢失或营养不良的情况。补充铁剂未导致风湿病情恶化。
