Weiss E, Berle P
Frauenklinik, Landeshauptstadt Wiesbaden.
Z Geburtshilfe Perinatol. 1991 Jan-Feb;195(1):37-42.
40 fetuses with diastolic zero flow or diastolic reverse flow of the umbilical arteries were examined in a longitudinal analysis. While 35 fetuses had to be delivered by cesarean section, three fetuses showed intrauterine death which seemed to be inevitable, and two fetuses were delivered vaginally without signs of fetal distress. In one third of our study group the cesarean section was necessary immediately after admittance to the obstetrical ward. The remaining two thirds were clinically observed up to one or up to four weeks respectively. The shorter the interval between diagnosis of the zero flow and delivery the larger was the gestational age, the amount of severe fetal acidosis, and the number of emergency cesarean section. The clinically observed groups were delivered significantly earlier and fetal blood gases were normal. Only one case of emergency cesarean section was observed. The bad fetal outcome of fetuses with diastolic zero flow of the umbilical arteries is therefore caused by the hypoxia and asphyxia of the not hospitalized and clinically observed high risk pregnancies. The early diagnosis of this flow pattern and the immediate clinical admittance and surveillance with doppler flow measurements and CTG-monitoring including the oxytocin challenge test allows to reduce the amount of fetal acidosis by adequate timing of the delivery. Acute placental insufficiency in cases with diastolic zero or reverse flow commonly occurs before the 33. week of pregnancy.
对40例脐动脉舒张末期血流为零或反向的胎儿进行了纵向分析。35例胎儿需剖宫产分娩,3例胎儿出现宫内死亡,似乎无法避免,2例胎儿经阴道分娩,无胎儿窘迫迹象。在我们的研究组中,三分之一的产妇在进入产科病房后立即进行了剖宫产。其余三分之二则分别进行了长达1周或4周的临床观察。脐动脉血流零值诊断与分娩之间的间隔越短,胎龄越大,严重胎儿酸中毒的程度越高,急诊剖宫产的次数越多。临床观察的组分娩时间明显提前,胎儿血气正常。仅观察到1例急诊剖宫产。因此,脐动脉舒张末期血流为零的胎儿不良结局是由未住院且未进行临床观察的高危妊娠的缺氧和窒息所致。这种血流模式的早期诊断以及通过多普勒血流测量和包括催产素激惹试验在内的CTG监测进行即时临床收治和监测,能够通过适当的分娩时机减少胎儿酸中毒的发生。脐动脉舒张末期血流为零或反向的病例中,急性胎盘功能不全通常发生在妊娠33周之前。