Suppr超能文献

中国海洛因依赖、美沙酮维持治疗吸烟者吸烟状况和动机的时间变化。

Temporal changes of smoking status and motivation among Chinese heroin-dependent, methadone-maintained smokers.

机构信息

Ningbo Addiction Research and Treatment Center, Ningbo University, PR China.

出版信息

Addict Behav. 2010 Oct;35(10):861-5. doi: 10.1016/j.addbeh.2010.05.003. Epub 2010 Jun 1.

Abstract

INTRODUCTION

The rates of cigarette smoking remain extremely high in active heroin users and methadone-maintained patients. It remains undetermined whether smoking status and motivation would be differentially affected by heroin and methadone administration.

METHODS

Heroin-dependent, methadone-maintained patients were recruited in the present studies. A battery of self-report questionnaires was used in the current study, in order to assess smoking status and motivations before first heroin use, during active heroin use and after Methadone Maintenance Treatment (MMT) admission.

RESULTS

An extremely high portion of participants started smoking before first heroin use. The highest level of cigarette smoking was found during the period of active heroin use, and cigarette consumption was reported to decrease after MMT admission. A wide range of smoking motivations were found before first heroin use. Moreover, "maintaining heroin pleasure" was the primary motivation for the increase in cigarette consumption during the period of active heroin use and 1h after heroin administration, while "habitual smoking" was the primary smoking motivation before first heroin use and after MMT admission respectively.

CONCLUSIONS

The present study first demonstrated that the prolonged rewarding effect of heroin following cigarette smoking may account for the increase of nicotine consumption found in the heroin-dependent patients. It appears that heroin and methadone differentially influenced smoking status and motivation among heroin-dependent, methadone-maintained patients.

摘要

简介

在活跃的海洛因使用者和美沙酮维持治疗患者中,吸烟率仍然极高。吸烟状况和动机是否会因海洛因和美沙酮给药而产生差异,目前仍不确定。

方法

本研究招募了海洛因依赖、美沙酮维持治疗的患者。目前的研究使用了一系列自我报告问卷,以评估首次使用海洛因之前、使用海洛因期间和接受美沙酮维持治疗(MMT)后的吸烟状况和动机。

结果

极高比例的参与者在首次使用海洛因之前就开始吸烟。在使用海洛因期间,吸烟量达到最高水平,在接受 MMT 后,吸烟量报告减少。在首次使用海洛因之前发现了广泛的吸烟动机。此外,“维持海洛因快感”是在使用海洛因期间和使用海洛因后 1 小时内增加吸烟量的主要动机,而“习惯性吸烟”则是首次使用海洛因前和接受 MMT 后的主要吸烟动机。

结论

本研究首次表明,吸烟后海洛因的长期奖赏作用可能是海洛因依赖患者尼古丁消耗增加的原因。海洛因和美沙酮似乎对海洛因依赖、美沙酮维持治疗患者的吸烟状况和动机有不同的影响。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验