如何使用计算环境R来分析三磷酸腺苷（ATP）诱导的核糖核苷酸还原酶R1六聚化数据。
How to use the computing environment R to analyze ATP-induced ribonucleotide reductase R1 hexamerization data.
作者信息
Radivoyevitch T
机构信息
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106, USA.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2010 Jun;29(4-6):427-32. doi: 10.1080/15257771003741174.
R is an object oriented free and open source statistical computing environment. The R package Combinatorially Complex Equilibrium Model Selection is being developed to meet the analysis challenges of ribonucleotide reductase (RNR). An example of its use is given here. This example involves ATP-induced R1 hexamerization dynamic light scattering data that suggests that R1 hexamers have two types of a-sites, one that binds ATP and another that does not (here, R1 is the large subunit of RNR).
R是一个面向对象的免费开源统计计算环境。正在开发R包“组合复杂平衡模型选择”以应对核糖核苷酸还原酶（RNR）的分析挑战。此处给出了一个使用示例。该示例涉及ATP诱导的R1六聚化动态光散射数据，这表明R1六聚体有两种类型的a位点，一种结合ATP，另一种不结合（此处，R1是RNR的大亚基）。
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