Chen Jian-Ling, Chou Yi-Hong, Tiu Chui-Mei, Chiou Hong-Jen, Wang Hsin-Kai, Chiou See-Ying, Liang I-Ping, Lee Chien-Ho, Chang Cheng-Yen
Department of Radiology, Veterans General Hospital-Taipei, and National Yang-Ming University, School of Medicine, Taipei, Taiwan.
J Clin Ultrasound. 2010 Jul;38(6):309-13. doi: 10.1002/jcu.20694.
To determine the incidence of testicular microlithiasis (TM) in Taiwanese males who were referred for scrotal sonography (US) and to evaluate the association between TM and cancer, with state-of-the-art equipment.
This retrospective study included 513 males who underwent scrotal US in a period of 7 months. The US images and charts of each patient were reviewed to determine the presence of TM and note relevant clinical information.
The data for all 513 patients were analyzed. Their age was 0-91 years (mean, 54.3 years). The overall incidence of TM was 14.4% (74/513); 6.2% (32/513) had classic TM, and 8.2% had limited TM. The incidence of testicular cancer in this population was 1.6% (8/513). Six of eight (75%) patients who had testicular cancer at presentation had classic TM or limited TM. There was a significant difference (P < 0.01) between the rate of malignancy in subjects with TM (6/74) and that in subjects without TM (2/439).
The incidence of TM in Taiwanese people may be higher than previously reported, which may be due to the difference in methodology and increased awareness of the US findings. Although there was a significant difference in the rate of malignancy in males with TM compared with those without TM, the question remains whether TM independently increases the risk of testicular malignancy.
使用先进设备，确定因阴囊超声检查（US）而转诊的台湾男性睾丸微结石症（TM）的发病率，并评估TM与癌症之间的关联。
这项回顾性研究纳入了513名在7个月内接受阴囊US检查的男性。回顾了每位患者的US图像和病历，以确定是否存在TM，并记录相关临床信息。
对所有513名患者的数据进行了分析。他们的年龄为0至91岁（平均54.3岁）。TM的总体发病率为14.4%（74/513）；6.2%（32/513）为典型TM，8.2%为局限性TM。该人群中睾丸癌的发病率为1.6%（8/513）。8名初诊时患有睾丸癌的患者中有6名（75%）患有典型TM或局限性TM。TM患者（6/74）和非TM患者（2/439）的恶性肿瘤发生率存在显著差异（P<0.01）。
台湾人群中TM的发病率可能高于先前报道，这可能是由于方法学差异以及对US检查结果的认识提高所致。尽管与无TM的男性相比，有TM的男性恶性肿瘤发生率存在显著差异，但TM是否独立增加睾丸恶性肿瘤风险的问题仍然存在。
