Rosenthal Lawrence S, Mester Steven, Rakovec Peter, Penaranda J Benezet, Sherman Jon R, Sheldon Todd J, Zeng Cathy, Wang Paul
UMassMemorial Medical Center, Worcester, Massachusetts, USA.
Pacing Clin Electrophysiol. 2010 Aug;33(8):1020-30. doi: 10.1111/j.1540-8159.2010.02809.x. Epub 2010 Jun 2.
The CAPTURE study evaluated the accuracy of automated atrial and right ventricular (RV) threshold algorithms.
Modern pacemakers include many added features designed to improve the ease of patient follow-up, as well as algorithms to reduce pacing outputs and/or reduce the atrial or ventricular pacing percentages, thus improving longevity.
Automated atrial and RV threshold measurements were assessed versus manual measurements at 6 months. The projected longevity was assessed and compared between subjects with the threshold-tracking feature On versus Off. In addition, the projected longevity effect of device features to reduce atrial pacing and reduce ventricular pacing, and device characteristics such as battery size and high impedance leads (> or =1,000 ohms), was investigated.
Atrial and RV manual versus automatic measurements were equivalent in 683 of 691 subjects (98.8%) and 736 of 746 subjects (98.7%), respectively. Thresholds were stable with 99.6% of atrial and 99.2% of RV consecutive measurements within +/-0.25V. Algorithms for threshold tracking, reducing ventricular pacing, and reducing atrial pacing were associated with 0.8, 0.9, and 0.2 years projected longevity improvements. High impedance leads were associated with a 0.8-year projected longevity improvement. Approximately 2 years of longevity improvement was projected for a 1-cc increase in device size.
The atrial and RV algorithms were accurate and reliable in all leads tested. Threshold tracking, reduced ventricular pacing, and high impedance leads result in increased device longevity. Battery capacity was the strongest determinant of increased projected longevity.
CAPTURE研究评估了自动心房和右心室（RV）阈值算法的准确性。
现代起搏器具有许多附加功能，旨在提高患者随访的便利性，还有算法可降低起搏输出和/或降低心房或心室起搏百分比，从而延长使用寿命。
在6个月时评估自动心房和RV阈值测量与手动测量的情况。对阈值跟踪功能开启和关闭的受试者之间的预计使用寿命进行评估和比较。此外，还研究了减少心房起搏和减少心室起搏的设备功能以及电池尺寸和高阻抗导线（≥1000欧姆）等设备特性对预计使用寿命的影响。
691名受试者中有683名（98.8%）、746名受试者中有736名（98.7%）的心房和RV手动测量与自动测量结果相当。阈值稳定，99.6%的心房连续测量值和99.2%的RV连续测量值在±0.25V范围内。阈值跟踪、减少心室起搏和减少心房起搏的算法分别与预计延长0.8年、0.9年和0.2年的使用寿命相关。高阻抗导线与预计延长0.8年的使用寿命相关。设备尺寸每增加1立方厘米，预计使用寿命可延长约2年。
在所有测试导线中，心房和RV算法准确可靠。阈值跟踪、减少心室起搏和高阻抗导线可延长设备使用寿命。电池容量是预计使用寿命增加的最强决定因素。
