Wales Institute of Cognitive Neuroscience, Bangor University, United Kingdom.
Brain Cogn. 2010 Aug;73(3):153-9. doi: 10.1016/j.bandc.2010.04.001. Epub 2010 May 23.
Electrophysiological and functional neuroimaging evidence points to the existence of neural populations that respond strongly and selectively to the appearance of the human body and its parts. However, the relationship between ERP and fMRI markers of these populations remains unclear. Here we used a previously identified functional dissociation between two body-selective regions identified with fMRI (extrastriate body area or EBA; fusiform body area or FBA) in order to better understand the source of a body-selective N1 ERP component. Specifically, we compared the magnitude of the N1 elicited by images of fingers, hands, arms and bodies to that obtained for hierarchically-matched control stimuli. We found close agreement between the pattern of body-part selectivity exhibited by N1, and the pattern of BOLD selectivity elicited in a previous study by the same type of stimuli in EBA (in contrast to FBA). We interpret these findings as evidence for EBA as the primary generator of the body-selective N1 component. Our results are an example of the use of functional criteria to distinguish among the possible neural sources of ERP markers.
电生理和功能神经影像学的证据表明,存在着对人体及其部位的出现有强烈而选择性反应的神经群体。然而,这些群体的 ERP 和 fMRI 标记物之间的关系尚不清楚。在这里,我们使用了先前在 fMRI 中确定的两个身体选择性区域(外梭状回身体区或 EBA;梭状回身体区或 FBA)之间的功能分离,以便更好地理解身体选择性 N1 ERP 成分的来源。具体来说,我们比较了手指、手、手臂和身体图像引起的 N1 的幅度,以及之前使用相同类型刺激在 EBA 中获得的分层匹配对照刺激引起的 N1 的幅度。我们发现,N1 表现出的身体部位选择性模式与之前在 EBA 中相同类型刺激引起的 BOLD 选择性模式非常吻合(与 FBA 相反)。我们将这些发现解释为 EBA 是身体选择性 N1 成分的主要产生源的证据。我们的结果是使用功能标准来区分 ERP 标记物的可能神经源的一个例子。