Service de rhumatologie A, hôpital Cochin, AP-HP, université Paris Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
Joint Bone Spine. 2010 Dec;77(6):611-3. doi: 10.1016/j.jbspin.2010.02.041. Epub 2010 Jun 2.
Coccidioidomycosis is a fungal disease caused by inhalation of airborne particles of Coccidioides spp. Coccidioidomycosis is endemic in several parts of the South-western US and South America. There are no symptoms in 60% of cases and, when symptoms exist, they usually consist of mild flu-like manifestations or mild lung disease. Disseminated coccidioidomycosis accounts for only 5% of symptomatic cases but can be life-threatening. The main targets of disseminated coccidioidomycosis are the skin, lymphoid tissue, central nervous system, and musculoskeletal system. Prolonged antifungal therapy is required and some patients may need surgical debridement. We report a case of disseminated spinal coccidioidomycosis in an immunocompetent patient.
球孢子菌病是一种真菌病，由吸入球孢子菌属的空气传播颗粒引起。球孢子菌病流行于美国西南部和南美洲的几个地区。60%的病例没有症状，而当出现症状时，通常表现为轻微的流感样症状或轻度肺部疾病。播散性球孢子菌病仅占有症状病例的 5%，但可能危及生命。播散性球孢子菌病的主要靶器官是皮肤、淋巴组织、中枢神经系统和肌肉骨骼系统。需要进行长期的抗真菌治疗，有些患者可能需要手术清创。我们报告了一例免疫功能正常患者的播散性脊髓球孢子菌病。
