Ries F, Beyenburg S, Jerusalem F
Neurologische Universitätsklinik Bonn.
Fortschr Neurol Psychiatr. 1991 Apr;59(4):141-6. doi: 10.1055/s-2007-1000687.
Cavernous angiomas, although rare, represent a clinical and a neuroradiological challenge in the differential diagnosis of cerebrovascular malformations. We report about three cases with a total of seven cavernous angiomas. Clinical features include intracerebral hemorrhage, epileptic seizures and focal neurological signs. Diagnosis is based on typical findings in MRI in combination with an angiography presenting a normal vascular situation or an avascular mass lesion, whereas CT-scan shows nonspecific features. Surgical removal is generally recommended, but could not be done in our cases. A histological verification of a clinically typical diagnosis is not mandatory. Indication for proton beam irradiation still has to be discussed. A definite therapeutical approach will have to consider the natural history in a larger number of cases.
海绵状血管瘤虽然罕见，但在脑血管畸形的鉴别诊断中是一个临床和神经放射学上的挑战。我们报告了3例共7个海绵状血管瘤的病例。临床特征包括脑出血、癫痫发作和局灶性神经体征。诊断基于MRI的典型表现，并结合血管造影显示正常血管情况或无血管肿块病变，而CT扫描显示非特异性特征。一般建议手术切除，但在我们的病例中无法进行。对临床典型诊断进行组织学验证并非必需。质子束照射的适应证仍有待讨论。明确的治疗方法将不得不考虑更多病例的自然病程。
