Ahangari Zohreh, Nasser Mona, Mahdian Mina, Fedorowicz Zbys, Marchesan Melissa A
Department of Endodontics and Iranian Dental Research Centre, Shahid Beheshti School of Dentistry, Daneshjou Boulevard, Evin, Tehran, Iran, 19834.
Cochrane Database Syst Rev. 2010 Jun 16(6):CD008003. doi: 10.1002/14651858.CD008003.pub2.
External root resorption is a pathological process which tends to occur following a wide range of mechanical or chemical stimuli such as infection, pressure, trauma or orthodontic tooth movement. Although it is predominantly detected by radiography, in some cases, root resorption may be identified by clinical symptoms i.e. pain, swelling and mobility of the tooth. Treatment alternatives are case-dependant and aim at the removal of the cause and the regeneration of the resorptive lesion.
To evaluate the effectiveness of any interventions that can be used in the management of external root resorption in permanent teeth.
We searched the following databases in April 2010: The Cochrane Oral Health Group's Trials Register; the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, Issue 3); MEDLINE (via OVID) (1950 to April 2010); and EMBASE (via OVID) (1980 to April 2010). We also searched two regional bibliographic databases (IndMED and Iranmedex) and handsearched five Iranian dental journals using free text terms appropriate for this review.
Randomised controlled trials comparing any type of intervention including root canal medications and canal filling, splinting or extraction of teeth or the surgical removal of any relevant pathology with each other, or placebo or no treatment applied to permanent teeth with any type of external root resorption which had been confirmed by clinical and radiological examination.
Two review authors conducted screening of studies in duplicate and independently. The Cochrane Collaboration statistical guidelines were to be followed.
66 trials were identified in our searches none of which matched our inclusion criteria. However, we identified one ongoing study which is potentially relevant to this review and will be assessed when it is published.
AUTHORS' CONCLUSIONS: We were unable to identify any reports of randomised controlled trials regarding the efficacy of different interventions for the management of external root resorption. In view of the lack of any high level evidence on this topic, it is suggested that clinicians decide on the most appropriate means of managing this condition according to their clinical experience with regard to patient related factors. Future research should consist of robust clinical trials which conform to the CONSORT statement (www.consort-statement.org/).
牙根外吸收是一种病理过程,往往在受到多种机械或化学刺激后发生,如感染、压力、创伤或正畸牙齿移动。虽然主要通过影像学检查发现,但在某些情况下,牙根吸收也可通过临床症状识别,如疼痛、肿胀和牙齿松动。治疗方案因具体病例而异,旨在消除病因并使吸收性病变再生。
评估可用于治疗恒牙牙根外吸收的任何干预措施的有效性。
我们于2010年4月检索了以下数据库:Cochrane口腔健康组试验注册库;Cochrane对照试验中央注册库(CENTRAL)(Cochrane图书馆2010年第3期);MEDLINE(通过OVID)(1950年至2010年4月);以及EMBASE(通过OVID)(1980年至2010年4月)。我们还检索了两个地区性书目数据库(IndMED和Iranmedex),并使用适合本综述的自由文本词对手工检索了五本伊朗牙科杂志。
随机对照试验,比较任何类型的干预措施,包括根管用药和根管充填、牙齿夹板固定或拔除,或手术切除任何相关病变,相互之间进行比较,或与安慰剂或未对经临床和影像学检查确诊的任何类型牙根外吸收的恒牙进行治疗进行比较。
两位综述作者进行了重复和独立的研究筛选。将遵循Cochrane协作组的统计指南。
我们在检索中识别出66项试验,其中没有一项符合我们的纳入标准。然而,我们识别出一项正在进行的研究,该研究可能与本综述相关,将在发表时进行评估。
我们未能找到关于不同干预措施治疗牙根外吸收疗效的随机对照试验报告。鉴于该主题缺乏任何高级别证据,建议临床医生根据其对患者相关因素的临床经验,决定治疗这种情况的最合适方法。未来的研究应包括符合CONSORT声明(www.consort-statement.org/)的严格临床试验。