中国418例疑似间质性肺疾病患者的外科肺活检。
Surgical lung biopsies in 418 patients with suspected interstitial lung disease in China.
作者信息
Zhang Deping, Liu Yin
机构信息
Department of Respiratory Medicine, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
出版信息
Intern Med. 2010;49(12):1097-102. doi: 10.2169/internalmedicine.49.3225. Epub 2010 Jun 15.
BACKGROUND
The present study was aimed to evaluate the role and safety of surgical lung biopsies (SLB) in patients with interstitial lung disease (ILD) in China.
METHODS
A retrospective analysis of 418 patients with ILD undergoing SLB from Chinese literature and the data of our hospital during the past ten years was performed.
RESULTS
A total of 418 cases underwent SLB, including open lung biopsy (OLB) in 229 cases and video-assisted thoracoscopic lung biopsy (VATLB) in 189 cases. SLB yielded a specific diagnosis for 88.0% cases, and unclassifiable idiopathic interstitial pneumonia diagnosis was seen in 9.1% cases. The total postoperative complication rate was 12.0% and mortality rate was 1.9%. The diagnostic yield, post-operative complication rate, and mortality rate between VATLB and OLB had no significant difference.
CONCLUSION
SLB is a very useful and relatively safe procedure for diagnosis of ILD.
背景
本研究旨在评估外科肺活检（SLB）在中国间质性肺疾病（ILD）患者中的作用及安全性。
方法
对过去十年来自中国文献及我院接受SLB的418例ILD患者进行回顾性分析。
结果
共418例患者接受了SLB，其中229例行开胸肺活检（OLB），189例行电视辅助胸腔镜肺活检（VATLB）。SLB对88.0%的病例做出了明确诊断，9.1%的病例诊断为无法分类的特发性间质性肺炎。术后总并发症发生率为12.0%，死亡率为1.9%。VATLB与OLB之间的诊断率、术后并发症发生率及死亡率无显著差异。
结论
SLB是诊断ILD的一种非常有用且相对安全的方法。
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