Department of Internal Medicine, University of Rochester Medical Center, Rochester, NY, USA.
J Cardiovasc Transl Res. 2009 Jun;2(2):150-3. doi: 10.1007/s12265-009-9093-x. Epub 2009 Mar 4.
The prevalence of resistant hypertension continues to increase and the standard approaches of therapeutic lifestyle changes and drug therapy are ineffective in bringing many of these patients to goal blood pressure. Electrical stimulation of the carotid sinus baroreceptor through a surgically implanted device is presently under clinical investigation and is showing some encouraging early results. This review discusses the evolution of this therapy including a review of the current data available from the early stages of ongoing clinical trials.
耐药性高血压的患病率持续上升,治疗性生活方式改变和药物治疗的标准方法对许多患者的血压达标无效。通过手术植入的装置对颈动脉窦压力感受器进行电刺激目前正在临床研究中,并显示出一些令人鼓舞的早期结果。本文讨论了这种治疗方法的发展,包括对正在进行的临床试验早期阶段现有数据的回顾。