Roukis Thomas S, Singh Niten, Andersen Charles A
Madigan Army Medical Center, Tacoma, Washington, USA.
Foot Ankle Spec. 2010 Aug;3(4):177-83. doi: 10.1177/1938640010374217. Epub 2010 Jun 18.
The authors performed a retrospective review of prospectively collected data of all diabetic patients who underwent transmetatarsal amputation (TMA) for toe gangrene or neuropathic ulceration from May 2006 to June 2009. Twenty-nine TMAs were performed in diabetic patients during the study period, including 24 men and 5 women with a mean +/- SD age of 66.3 +/- 7.5 years. The indications for TMA were gangrene of > or = 2 digits in 12 patients (41%) and neuropathic ulceration with underlying osteomyelitis or abscess and a concomitant dysfunctional forefoot in 17 patients (59%). Of the 12 patients who presented with toe gangrene, 7 (58%) underwent endovascular intervention and 5 (42%) underwent open vascular bypass. Equinus contracture was present in 27 patients (93%), and 26 (96%) of these patients underwent tendo-Achilles lengthening or gastrocnemius recession. Correction of equinus contracture was not performed in 1 patient as it was deemed not feasible. Forefoot varus deformity was present in 22 (76%) patients, and balancing was performed in 17 of these patients (77%) with skeletal stabilization or tendon transfer. Balancing was not performed in the remaining patients as it was not necessary or not feasible. Sixteen patients (55%) healed primarily and 5 patients (17%) developed minor wound separation that healed via secondary intention. An additional 4 patients were able to maintain functional revision procedures confined to the foot (1 TMA revision, 3 Chopart amputations). Three patients (10%) required below-knee amputation, and there were 2 deaths (7%) during the time period. Functional amputation confined to the foot was achieved in 86% of ambulatory diabetic patients. These results support a more aggressive initial approach in ambulatory diabetic patients with multiple digital ulcerations, allowing this patient population to remain functional and avoid multiple reoperations and ultimately major amputation.
作者对2006年5月至2009年6月期间因趾坏疽或神经性溃疡而接受经跖骨截肢(TMA)的所有糖尿病患者的前瞻性收集数据进行了回顾性分析。在研究期间,对29例糖尿病患者进行了TMA,其中包括24名男性和5名女性,平均年龄为66.3±7.5岁。TMA的指征为12例患者(41%)有≥2个趾的坏疽,17例患者(59%)为伴有潜在骨髓炎或脓肿以及前足功能障碍的神经性溃疡。在出现趾坏疽的12例患者中,7例(58%)接受了血管内介入治疗,5例(42%)接受了开放血管搭桥术。27例患者(93%)存在马蹄足挛缩,其中26例(96%)患者接受了跟腱延长或腓肠肌松解术。1例患者因认为不可行而未进行马蹄足挛缩矫正。22例(76%)患者存在前足内翻畸形,其中17例(77%)患者通过骨骼稳定或肌腱转移进行了平衡矫正。其余患者因不必要或不可行而未进行平衡矫正。16例患者(55%)一期愈合,5例患者(17%)出现轻度伤口裂开,经二期愈合。另外4例患者能够维持仅限于足部的功能性翻修手术(1例TMA翻修,3例Chopart截肢)。3例患者(10%)需要膝下截肢,在此期间有2例死亡(7%)。86%的非卧床糖尿病患者实现了仅限于足部的功能性截肢。这些结果支持对患有多个趾溃疡的非卧床糖尿病患者采取更积极的初始治疗方法,使该患者群体保持功能,避免多次再次手术并最终避免大截肢。