色素性多形性黄色星形细胞瘤：一种罕见的变异型并文献复习。

Pigmented pleomorphic xanthoastrocytoma: a rare variant and literature review.

机构信息

Department of Neuropathology, Institute of Neurology, Huashan Hospital of Fudan University, Shanghai, China.

出版信息

Neuropathology. 2011 Feb;31(1):88-92. doi: 10.1111/j.1440-1789.2010.01132.x.

DOI:10.1111/j.1440-1789.2010.01132.x

PMID:20573030

Abstract

A 16-year-old male teenager presented with seizure and loss of consciousness for 20 min. Magnetic resonance imaging demonstrated a mass occupying the right medial temporal lobe. Histological examination revealed a non-pigmented area with spindle-shaped and large xanthomatous pleomorphic cells and a pigmented region with pigmented neoplastic cells with fascicular arrangement. Immunohistochemical studies showed the tumor was positive for GFAP and low index of Ki-67. Considering the patient's history, clinical data and pathological findings, we rendered a rare variant named pigmented pleomorphic xanthoastrocytoma.

摘要

一位 16 岁的男性青少年因癫痫发作和意识丧失 20 分钟就诊。磁共振成像显示一个占据右侧内侧颞叶的肿块。组织学检查显示一个无色素区域，有梭形和大黄色瘤样多形性细胞，以及一个有色素的区域，有束状排列的色素性肿瘤细胞。免疫组织化学研究显示肿瘤对 GFAP 呈阳性，Ki-67 指数较低。考虑到患者的病史、临床数据和病理发现，我们诊断为一种罕见的变异型，命名为色素性多形性黄色星形细胞瘤。