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先前的自然流产或人工流产经历与随后妊娠期间创伤后应激和抑郁的风险。

Previous experience of spontaneous or elective abortion and risk for posttraumatic stress and depression during subsequent pregnancy.

机构信息

University of Michigan, Ann Arbor, 48109-1290, USA.

出版信息

Depress Anxiety. 2010 Aug;27(8):699-707. doi: 10.1002/da.20714.

Abstract

BACKGROUND

Few studies have considered whether elective and/or spontaneous abortion (EAB/SAB) may be risk factors for mental health sequelae in subsequent pregnancy. This paper examines the impact of EAB/SAB on mental health during subsequent pregnancy in a sample of women involved in a larger prospective study of posttraumatic stress disorder (PTSD) across the childbearing year (n=1,581).

METHODS

Women expecting their first baby completed standardized telephone assessments including demographics, trauma history, PTSD, depression, and pregnancy wantedness, and religiosity.

RESULTS

Fourteen percent (n=221) experienced a prior elective abortion (EAB), 13.1% (n=206) experienced a prior spontaneous abortion (SAB), and 1.4% (n=22) experienced both. Of those women who experienced either an EAB or SAB, 13.9% (n=220) appraised the EAB or SAB experience as having been "a hard time" (i.e., potentially traumatic) and 32.6% (n=132) rated it as their index trauma (i.e., their worst or second worst lifetime exposure). Among the subset of 405 women with prior EAB or SAB, the rate of PTSD during the subsequent pregnancy was 12.6% (n-51), the rate of depression was 16.8% (n=68), and 5.4% (n-22) met criteria for both disorders.

CONCLUSIONS

History of sexual trauma predicted appraising the experience of EAB or SAB as "a hard time." Wanting to be pregnant sooner was predictive of appraising the experience of EAB or SAB as the worst or second worst (index) trauma. EAB or SAB was appraised as less traumatic than sexual or medical trauma exposures and conveyed relatively lower risk for PTSD. The patterns of predictors for depression were similar.

摘要

背景

很少有研究考虑选择性和/或自发性流产(EAB/SAB)是否可能成为随后妊娠心理健康后遗症的风险因素。本文在一项关于创伤后应激障碍(PTSD)的更大前瞻性研究样本中,研究了 EAB/SAB 对随后妊娠期间心理健康的影响(n=1581)。

方法

期待第一个孩子的女性通过标准化电话评估完成人口统计学、创伤史、PTSD、抑郁和怀孕意愿以及宗教信仰的评估。

结果

14%(n=221)经历过选择性流产(EAB),13.1%(n=206)经历过自发性流产(SAB),1.4%(n=22)经历过两者。在经历过 EAB 或 SAB 的女性中,13.9%(n=220)认为 EAB 或 SAB 经历是“困难时期”(即潜在的创伤),32.6%(n=132)将其评定为指数创伤(即一生中最严重或第二严重的创伤)。在经历过 EAB 或 SAB 的 405 名女性中,随后妊娠期间 PTSD 的发生率为 12.6%(n=51),抑郁的发生率为 16.8%(n=68),有 5.4%(n=22)同时符合这两种疾病的标准。

结论

性创伤史预测了将 EAB 或 SAB 经历评定为“困难时期”。希望更早怀孕预测了将 EAB 或 SAB 经历评定为最严重或第二严重(指数)创伤。EAB 或 SAB 被评定为比性或医疗创伤暴露创伤性较小,并且与 PTSD 的风险相对较低相关。抑郁的预测因素模式相似。

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