病理预后评分作为预测胃癌预后的简单标准。
Pathological prognostic score as a simple criterion to predict outcome in gastric carcinoma.
机构信息
Department of Surgery, Fukuoka Higashi Medical Center, Chidori, Koga, Japan.
出版信息
J Surg Oncol. 2010 Jul 1;102(1):73-6. doi: 10.1002/jso.21586.
PURPOSE
The aim of this study was to establish a simple criterion to predict prognosis of patients with gastric carcinoma.
METHODS
Two hundred four patients with gastric carcinoma, who had been treated with curative resection, were enrolled. One point was added for each category among four pathological factors of depth of tumor, lymph node metastasis, venous invasion, and lymphatic invasion. Pathological Prognostic Score (PPS) was determined by an aggregate of these points for each category.
RESULTS
There existed a significant difference between survivals of patients with PPS 0 or 1 and 2 or 3 (P = 0.0002). Similarly, there also existed a significant difference between survivals of patients with PPS 2 or 3 and 4 (P = 0.010).
CONCLUSIONS
PPS can be quite simple criteria to predict prognosis of gastric carcinoma with a strict stratification.
目的
本研究旨在建立一种简单的标准，以预测胃癌患者的预后。
方法
纳入 204 例接受根治性切除术治疗的胃癌患者。在肿瘤深度、淋巴结转移、静脉侵犯和淋巴浸润四个病理因素中，每一类增加 1 分。通过对每一类的这些积分进行汇总，确定病理预后评分（PPS）。
结果
PPS 为 0 或 1 的患者的生存率与 PPS 为 2 或 3 的患者存在显著差异（P = 0.0002）。同样，PPS 为 2 或 3 的患者的生存率与 PPS 为 4 的患者也存在显著差异（P = 0.010）。
结论
PPS 是一种预测胃癌预后的简单标准，可以进行严格分层。
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