NMR 研究氯仿和隐穴醚 C 之间的主客体配合物。

NMR investigation of guest-host complex between chloroform and cryptophane C.

机构信息

Department of Materials and Environmental Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden.

出版信息

Magn Reson Chem. 2010 Aug;48(8):623-9. doi: 10.1002/mrc.2637.

DOI:10.1002/mrc.2637

PMID:20589729

Abstract

Guest-host complex between cryptophane C, possessing two non-equivalent caps, and chloroform is investigated by NMR spectroscopy. The kinetics of the chloroform exchange between the bound and free sites is determined by (1)H exchange spectroscopy. Moreover, the preferential orientation of chloroform molecule with respect to the cryptophane C frame is examined by the NOESY and ROESY experiments. The experimental findings are compared to the results of quantum chemical calculations.

摘要

用 NMR 光谱法研究了具有两个不等价盖子的隐杯烯 C 与氯仿之间的主客体配合物。通过 (1)H 交换光谱法确定了结合位和游离位之间氯仿交换的动力学。此外，通过 NOESY 和 ROESY 实验研究了氯仿分子相对于隐杯烯 C 骨架的优先取向。实验结果与量子化学计算结果进行了比较。