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鼻胆管引流对于急性化脓性胆管炎的引流是否必要?我们的经验。

Is nasobiliary drainage unnecessary for drainage of acute suppurative cholangitis? Our experience.

机构信息

Department of Gastroenterology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

出版信息

Dig Endosc. 2010 Jul;22 Suppl 1:S118-22. doi: 10.1111/j.1443-1661.2010.00959.x.

Abstract

Two randomized controlled trials comparing endoscopic nasobiliary drainage (ENBD) and internal endoscopic biliary drainage (internal EBD) for acute suppurative cholangitis (ASC) showed no significant difference in efficacy and both preferred internal EBD to ENBD. In this study, the necessity of ENBD was re-examined. Over five years, 59 patients underwent an emergency endoscopic procedure for ASC in our institute. If drainage was needed, we selected internal EBD as a first choice and ENBD was used in patients predicted to have early obstruction of the tube or retrograde infection of the bile duct. The rate of ENBD, for which reason ENBD was selected, and the efficacy of drainage were examined retrospectively. In the 59 patients, 40 patients had the stones completely removed without drainage, five internal EBD and two ENBD were performed without removal of stones and five internal EBD and seven ENBD were performed after removal of stones. In terms of white blood cell count and direct bilirubin level, no significant difference was observed between ENBD and internal EBD patients. ENBD was mainly selected for the patients with multiple biliary strictures, hemorrhage tendency and excessive purulent bile. Even though internal drainage is suitable in many ASC patients, ENBD is necessary in selected patients.

摘要

两篇比较内镜鼻胆管引流(ENBD)和内镜内胆管引流(internal EBD)治疗急性化脓性胆管炎(ASC)的随机对照试验显示,两种方法在疗效上没有显著差异,而且都倾向于 internal EBD 而不是 ENBD。本研究重新检查了 ENBD 的必要性。在五年多的时间里,我院有 59 例 ASC 患者接受了紧急内镜治疗。如果需要引流,我们选择 internal EBD 作为首选,而对于预计管内早期阻塞或逆行胆管感染的患者,则使用 ENBD。回顾性检查了 ENBD 的使用率、选择 ENBD 的原因以及引流的效果。在这 59 例患者中,40 例患者的结石完全清除,无需引流,5 例患者进行了 internal EBD,2 例患者进行了 ENBD,且未取出结石,5 例患者进行了 internal EBD,7 例患者进行了 ENBD 以取出结石。在白细胞计数和直接胆红素水平方面,ENBD 患者和 internal EBD 患者之间没有显著差异。ENBD 主要用于有多处胆管狭窄、有出血倾向和脓性胆汁过多的患者。尽管许多 ASC 患者适合进行内部引流,但在某些选定的患者中,ENBD 是必要的。

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