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沙门氏菌性脓性肌炎并发镰状细胞贫血:一例报告

Salmonella pyomyositis complicating sickle cell anemia: a case report.

作者信息

Wong Vanessa K, Lissack Maxine E, Turmezei Tom D, Maitland Jenny A

机构信息

Department of Microbiology, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK.

出版信息

J Med Case Rep. 2010 Jun 30;4:198. doi: 10.1186/1752-1947-4-198.

Abstract

INTRODUCTION

Pyomyositis is a bacterial infection of skeletal muscle and a rare complication of sickle cell anemia. It may present a difficult problem in diagnosis, leading to delay in appropriate treatment and development of complications including abscess formation and osteomyelitis.

CASE PRESENTATION

We report the case of a 44-year-old Afro-Caribbean woman with homozygous sickle cell disease who presented with chest crisis and later developed pyomyositis of her hip and pelvic muscles. Salmonella agbeni was isolated from blood cultures and magnetic resonance imaging confirmed the diagnosis in this case. It is noteworthy of this case that there were no antecedent signs of gastroenteritis. Drainage was not appropriate and she was treated with intravenous antibiotics for six weeks.

CONCLUSIONS

Focal Salmonella infections are uncommon in soft tissue. Pyomyositis should be considered in patients with sickle cell anemia that continue to have muscle pain and high fevers, despite initial management of their sickle cell crisis. Radiological imaging, particularly magnetic resonance imaging, is a crucial tool in establishing the diagnosis.

摘要

引言

脓性肌炎是骨骼肌的细菌感染,是镰状细胞贫血的一种罕见并发症。它可能在诊断上存在难题,导致适当治疗的延迟以及包括脓肿形成和骨髓炎在内的并发症的发生。

病例报告

我们报告一例44岁的非洲加勒比裔女性,患有纯合子镰状细胞病,最初表现为胸部危象,随后发展为臀部和骨盆肌肉的脓性肌炎。血液培养分离出阿贝尼沙门氏菌,磁共振成像确诊了该病例。该病例值得注意的是没有前期胃肠炎的迹象。引流不合适,她接受了六周的静脉抗生素治疗。

结论

局灶性沙门氏菌感染在软组织中并不常见。对于镰状细胞贫血患者,尽管对镰状细胞危象进行了初始治疗,但如果持续存在肌肉疼痛和高热,应考虑脓性肌炎。放射学成像,尤其是磁共振成像,是确立诊断的关键工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfbb/2904793/94e739179a98/1752-1947-4-198-1.jpg

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