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结直肠癌筛查:粪便潜血试验的检出率

Colorectal cancer screening: yield of faecal occult blood testing.

作者信息

Teoh Mei Lin, Puvan R, Cheah P Y, Yuen Y

机构信息

Department of Family Medicine and Continuing Care, Singapore General Hospital, Singapore.

出版信息

Asian Pac J Cancer Prev. 2010;11(1):153-6.

Abstract

The incidence of colorectal cancer is rising and increasing public awareness of this condition has stimulated interest in screening tests. Colorectal cancer is treatable and curable in its early stages and clear benefits are present if the cancer can be detected in its early stages. Sensitivity of the faecal occult blood test (FOBT) by immunochemical techniques for colorectal (CRC) cancer screening has been reported as 67% to 89% in certain population screening programs. Although much work has been done to address screening of colorectal cancer in the community, not much has been done to establish what the expected outcomes of screening are in a cohort of voluntary asymptomatic individuals. This paper retrospectively reviews the findings in such a cohort who sought health assessment (including a FOBT) at a Health Screening Centre in a tertiary hospital in Singapore over the period of 2002 to 2007. The outcomes are discussed together with references to other relevant studies on faecal occult blood test screening of CRC.

摘要

结直肠癌的发病率正在上升,公众对这种疾病认识的提高激发了对筛查测试的兴趣。结直肠癌在早期是可治疗且可治愈的,如果能在早期检测到癌症,会有明显的益处。在某些人群筛查项目中,免疫化学技术粪便潜血试验(FOBT)用于结直肠癌(CRC)筛查的灵敏度据报道为67%至89%。尽管在社区中针对结直肠癌筛查已开展了大量工作,但对于自愿无症状个体队列中筛查的预期结果却没有做太多研究。本文回顾了2002年至2007年期间在新加坡一家三级医院的健康筛查中心寻求健康评估(包括FOBT)的此类队列的研究结果。同时结合其他关于粪便潜血试验筛查CRC的相关研究对结果进行了讨论。

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