Bull World Health Organ. 1961;25(6):831-50.
In economically under-developed countries in Africa the housing conditions, even in areas of low population density, can generally be described as overcrowded: also, they are usually poorly lighted and ill-ventilated. Malnutrition, especially protein lack, is quite common. It was considered important to assess the risk experienced under these circumstances by household contacts of sputum-positive tuberculosis patients.It was found that household contacts, especially of the younger age-groups, were infected five to ten times more frequently and experienced a prevalence of active pulmonary tuberculosis five to ten times greater than did the general population from which they derived.Examination of household contacts of tuberculosis patients as defined in this study revealed a further 15% of sputum-positive tuberculosis cases-a finding that underlines the importance of carrying out such a procedure as a routine measure.
在非洲经济欠发达的国家,即使在人口密度低的地区,住房条件通常也可以说是拥挤不堪:而且,这些住房往往采光和通风不良。营养不良,尤其是蛋白质缺乏,相当普遍。人们认为,评估痰检阳性肺结核患者家庭接触者在这种情况下所面临的风险非常重要。结果发现,家庭接触者,尤其是年龄较小的群体,受到感染的频率要高出五至十倍,患活动性肺结核的比例也要高出五至十倍,而这些接触者是从他们所在的人群中抽取的。对本研究中定义的肺结核患者的家庭接触者进行检查,又发现了 15%的痰检阳性肺结核病例——这一发现强调了将这种检查作为常规措施的重要性。