用 64 排多层螺旋 CT（MDCT）检测主动脉瓣反流。

Detection of aortic regurgitation with 64-slice multidetector computed tomography (MDCT).

机构信息

Division of Cardiology Los Angeles Biomedical Research Institute Harbor-UCLA, Torrance, CA, USA.

出版信息

Acad Radiol. 2010 Aug;17(8):1006-11. doi: 10.1016/j.acra.2010.04.007.

DOI:10.1016/j.acra.2010.04.007

PMID:20605488

Abstract

RATIONALE AND OBJECTIVES

To determine the diagnostic accuracy of 64-row multidetector cardiac computed tomography (MDCT) in detecting aortic regurgitation (AR) on prospectively acquired images with trans-thoracic echocardiography (TTE) as a reference standard.

MATERIALS AND METHODS

Forty-three consecutive patients underwent MDCT and TTE. AR was defined on MDCT images acquired at 75% phase of R-R interval as the lack of aortic cusps coaptation. The maximum regurgitant orifice area (ROA) was planimetered and compared to TTE.

RESULTS

All 29 patients with AR on TTE were correctly identified by MDCT. The sensitivity, specificity, positive predictive value, and negative predictive value of MDCT were 100%, 85.7%, 93.5%, and 100%, respectively. Sixteen, nine, and four patients were found to have mild, moderate, and severe AR on TTE, respectively. The corresponding ROA by MDCT were 3.25 +/- 1.04 mm(2), 4.16 +/- 1.19 mm(2), and 11.30 +/- 6.13 mm(2), respectively.

CONCLUSION

MDCT data acquired for the coronary artery evaluation can be used for the detection of aortic regurgitation with high diagnostic accuracy without additional scanning or radiation and can support appropriate referral for TTE.

摘要

目的

以经胸超声心动图（TTE）为参考标准，确定前瞻性采集图像的 64 排多层 CT（MDCT）检测主动脉瓣反流（AR）的诊断准确性。

材料和方法

连续 43 例患者接受 MDCT 和 TTE 检查。在 75%的 R-R 间期相位上获取 MDCT 图像，将主动脉瓣无瓣叶对合定义为 AR。通过描记法测量最大反流口面积（ROA），并与 TTE 进行比较。

结果

MDCT 正确识别了所有 29 例 TTE 阳性的 AR 患者。MDCT 的敏感性、特异性、阳性预测值和阴性预测值分别为 100%、85.7%、93.5%和 100%。TTE 分别发现 16、9 和 4 例患者为轻度、中度和重度 AR。MDCT 对应的 ROA 分别为 3.25±1.04mm²、4.16±1.19mm²和 11.30±6.13mm²。