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心脏监测:一项由初级保健机构实施的心血管疾病二级预防计划对药物使用和风险因素状况的影响。

Heartwatch: the effect of a primary care-delivered secondary prevention programme for cardiovascular disease on medication use and risk factor profiles.

作者信息

Fitzpatrick Patricia, Fitz-Simon Nicola, Lonergan Moira, Collins Claire, Daly Leslie

机构信息

School of Public Health, Physiotherapy and Population Science, University College Dublin, Ireland.

出版信息

Eur J Cardiovasc Prev Rehabil. 2011 Feb;18(1):129-35. doi: 10.1097/HJR.0b013e32833cca7d.

Abstract

BACKGROUND

Heartwatch is a secondary prevention programme of coronary heart disease (CHD) in primary care in Ireland. The aim was to further examine the effect of the Heartwatch programme on cardiovascular risk factors and treatments of patients with a follow-up of 3.5 years.

DESIGN

Prospective cohort study of 12,358 patients with established CHD (myocardial infarction, percutaneous cardiac intervention, coronary artery bypass graft) recruited by participating general practitioners; patients invited to attend on a quarterly basis, with continuing care implemented according to defined clinical protocols.

METHODS

Changes in risk factors and treatments at 1, 2, 3 and 3.5-year follow-up from baseline were made using paired t-test for continuous and McNemar's test for categorical data.

RESULTS

Important changes in systolic and diastolic blood pressure, total and low-density lipoprotein cholesterol and smoking status were observed at 1, 2, 3 and 3.5 years (P < 0.0001) with significant increase in proportions of patients within the target. However, changes in body mass index were small, with no significant improvement in waist circumference. There was a significant increase in prescription of secondary preventive medications and good patient compliance. Males were more likely to be within the target for systolic blood pressure, total cholesterol, waist circumference and exercise level at 3.5 years, but less likely for body mass index.

CONCLUSION

Studies of cardiac rehabilitation without any follow-up programmes show that over time patients revert in part to previous lifestyle habits; this primary care-delivered programme has shown sustained improvements in major risk factors, particularly smoking, blood pressure and cholesterol, and treatments for CHD. Weight management presents a greater challenge.

摘要

背景

“心脏监测”是爱尔兰基层医疗中冠心病二级预防项目。目的是进一步研究“心脏监测”项目对心血管危险因素及患者治疗的影响,随访时间为3.5年。

设计

对参与研究的全科医生招募的12358例确诊冠心病患者(心肌梗死、经皮心脏介入治疗、冠状动脉搭桥术)进行前瞻性队列研究;邀请患者每季度就诊一次,并根据既定临床方案提供持续护理。

方法

采用配对t检验分析连续变量在基线、1年、2年、3年和3.5年随访时危险因素及治疗情况的变化,采用McNemar检验分析分类变量的变化。

结果

在1年、2年、3年和3.5年时观察到收缩压和舒张压、总胆固醇和低密度脂蛋白胆固醇以及吸烟状况有显著变化(P < 0.0001),达到目标值的患者比例显著增加。然而,体重指数变化较小,腰围无显著改善。二级预防药物处方显著增加,患者依从性良好。在3.5年时,男性更有可能达到收缩压、总胆固醇、腰围和运动水平的目标值,但达到体重指数目标值的可能性较小。

结论

没有任何随访计划的心脏康复研究表明,随着时间推移,患者部分会恢复以前的生活方式;这个由基层医疗提供的项目在主要危险因素,特别是吸烟、血压和胆固醇以及冠心病治疗方面显示出持续改善。体重管理面临更大挑战。

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