Department of Anesthesia, Herzzentrum Lahr/Baden, Lahr, Germany.
Ann Thorac Surg. 2010 Jul;90(1):276-7. doi: 10.1016/j.athoracsur.2010.01.076.
A patient with impaired left ventricular function was scheduled for coronary artery bypass grafting. The patient's history revealed a life-threatening allergy to fish proteins. Therefore, because of the threat of cross-reactivity to protamine, a standard anticoagulation protocol with heparin/protamine was disapproved. Instead, complete coronary artery revascularization was successfully performed off-pump using bivalirudin as the anticoagulant.
一位左心室功能受损的患者被安排进行冠状动脉旁路移植术。该患者的病史显示其对鱼蛋白有危及生命的过敏反应。因此,由于对鱼精蛋白发生交叉反应的威胁,肝素/鱼精蛋白的标准抗凝方案被否决。取而代之的是,使用比伐卢定作为抗凝剂,在非体外循环下成功地完成了完全冠状动脉血运重建。