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带垫片褥式缝合减少腹腔镜 Nissen 胃底折叠术后反流复发。

Pledgeted mattress sutures reduce recurrent reflux after laparoscopic Nissen fundoplication.

机构信息

Division of Pediatric Surgery, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA.

出版信息

J Pediatr Surg. 2010 Jun;45(6):1159-64. doi: 10.1016/j.jpedsurg.2010.02.080.

Abstract

INTRODUCTION

In response to a perceived increase in the incidence of recurrent reflux after adopting the laparoscopic Nissen fundoplication, we adjusted our technique to include the use of pledgeted, horizontal mattress sutures for crural closure and wrap construction.

METHODS

We assessed the impact of this technical modification in children who underwent laparoscopic fundoplication between 1997 and 2007 at a large children's hospital. The medical history, indications, technical details, and outcomes were reviewed. Differences between groups were assessed with chi(2), logistic regression, and Kaplan-Meier analysis.

RESULTS

A total of 384 subjects were identified. Neurologic deficits were present in 77%. The crural closure and wrap were constructed with simple sutures in 226 and with pledgeted, horizontal mattress sutures in 158. The cumulative incidences of recurrent reflux, gagging/retching, wrap failure on imaging studies, and reoperation were significantly greater with the use of simple sutures (P < .01, .03, < .01, and < .01, respectively). Kaplan-Meier analysis confirmed a significant difference in the probability of recurrent reflux with simple sutures despite a significant difference in postoperative follow-up. Operative time was the same with both methods.

CONCLUSIONS

The use of pledgeted, horizontal mattress sutures for crural closure and wrap construction in laparoscopic Nissen fundoplication may reduce the incidence of recurrent reflux.

摘要

简介

为了应对腹腔镜 Nissen 胃底折叠术(LF)后复发性反流发生率增加的问题,我们调整了手术技术,在胃底折叠术时使用带垫片的水平褥式缝合来关闭胃底折叠术的胃底和包绕。

方法

我们在一家大型儿童医院评估了 1997 年至 2007 年间接受腹腔镜胃底折叠术的儿童中这一技术改进的效果。我们回顾了病史、适应证、技术细节和结果。采用卡方检验、逻辑回归和 Kaplan-Meier 分析评估组间差异。

结果

共纳入 384 例患者,其中 77%存在神经功能障碍。226 例使用单纯缝线进行胃底折叠术的胃底和包绕,158 例使用带垫片的水平褥式缝合进行胃底折叠术的胃底和包绕。单纯缝线组复发性反流、呛咳/呕吐、影像学研究显示包绕失败和再次手术的累积发生率显著更高(P <.01,.03, <.01 和 <.01)。Kaplan-Meier 分析证实,尽管术后随访时间存在显著差异,但单纯缝线组的复发性反流概率存在显著差异。两种方法的手术时间相同。

结论

腹腔镜 Nissen 胃底折叠术时使用带垫片的水平褥式缝合进行胃底折叠术的胃底和包绕可能会降低复发性反流的发生率。

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