Suppr超能文献

鼻炎对儿童哮喘控制的影响:与呼出一氧化氮(FeNO)的关联。

Impact of rhinitis on asthma control in children: association with FeNO.

作者信息

Chiron Raphael, Vachier Isabelle, Khanbabaee Ghamartaj, Molinari Nicolas, Varrin Muriel, Godard Philippe, Chanez Pascal

机构信息

Department of Respiratory Diseases, CHU Montpellier, Hospital Arnaud de Villeneuve, Montpellier, France.

出版信息

J Asthma. 2010 Aug;47(6):604-8. doi: 10.3109/02770901003759402.

Abstract

BACKGROUND

The prevalence of rhinitis is high and frequently observed in association with asthma. Although the persistence of predisposing factors such as rhinitis is frequently observed in adults, this has not yet been confirmed in children.

AIMS

The aim of this present work is to show the relationship between rhinitis and asthma control in asthmatic children.

METHODS

The authors carried out a cross-sectional study by collecting clinical, spirometric, and fractional exhaled nitric oxide (FeNO) data in children aged from 4 to 17 years.

RESULTS

One hundred seventeen children were included. Asthma control was optimal in 37.6%, suboptimal in 55.5% and poor in 7.3% of cases. A 74.3% of children were atopic and 62.5% had symptoms 34 of rhinitis. Rhinitis was more frequent when control of asthma was worse (p = .0001). Age (p = .002), asthma control (p < .001), atopy (p = .001), and presence of rhinitis (p = .012) were significantly associated with FeNO.

CONCLUSIONS

Our study confirms the strong relationship between upper airways and poor asthma control in the asthmatic child. Symptoms of rhinitis may be partly responsible for the increased fractional exhaled nitric oxide (FeNO) level, independently of the control of asthma. Evaluation of rhinitis should be included to improve assessment of asthma control in children.

摘要

背景

鼻炎患病率很高,且常与哮喘相关。尽管在成人中经常观察到鼻炎等诱发因素持续存在,但在儿童中尚未得到证实。

目的

本研究旨在揭示哮喘儿童鼻炎与哮喘控制之间的关系。

方法

作者开展了一项横断面研究,收集了4至17岁儿童的临床、肺功能和呼出一氧化氮分数(FeNO)数据。

结果

纳入了117名儿童。37.6%的病例哮喘控制良好,55.5%控制欠佳,7.3%控制较差。74.3%的儿童为特应性体质,62.5%有鼻炎症状。哮喘控制越差,鼻炎越常见(p = 0.0001)。年龄(p = 0.002)、哮喘控制情况(p < 0.001)、特应性体质(p = 0.001)和鼻炎的存在(p = 0.012)与FeNO显著相关。

结论

我们的研究证实了哮喘儿童上呼吸道与哮喘控制不佳之间的密切关系。鼻炎症状可能是呼出一氧化氮分数(FeNO)水平升高的部分原因,与哮喘控制无关。应纳入鼻炎评估以改善对儿童哮喘控制的评估。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验