Department of Pediatrics, Yuzuncu Yil University School of Medicine, Van, Turkey.
J Dermatol. 2010 Jul;37(7):671-3. doi: 10.1111/j.1346-8138.2010.00840.x.
Necrotizing fasciitis (NF) is a severe life-threatening soft tissue infection characterized by rapidly spreading necrosis of the fascia and the subcutaneous tissue. The initial skin presentation ranges from minimal rash to cellulites. The lesions subsequently spread rapidly. Even with appropriate medical and surgical therapy, the mortality rate in NF is more than 50%. In cases of neonates, mortality rate is higher than that ratio. High index of suspicion, prompt aggressive surgery, appropriate antibiotics and supportive care are the mainstays of management in the newborn infant with NF. Herein, we report a case of invasive and mortal NF caused by Staphylococcus epidermidis in an infant with extremely low birthweight.
坏死性筋膜炎(NF)是一种严重的、危及生命的软组织感染,其特征为筋膜和皮下组织迅速扩散性坏死。最初的皮肤表现从轻微皮疹到蜂窝织炎不等。病变随后迅速扩散。即使进行适当的医疗和手术治疗,NF 的死亡率也超过 50%。在新生儿中,死亡率高于该比例。在患有 NF 的新生儿中,高度怀疑、迅速积极的手术、适当的抗生素和支持性护理是治疗的主要方法。在此,我们报告了一例极低出生体重儿由表皮葡萄球菌引起的侵袭性和致命性 NF 病例。