首发住院后甲基苯丙胺所致精神病患者的长期结局。

Long-term outcomes in methamphetamine psychosis patients after first hospitalisation.

机构信息

Advisory Office, Department of Mental Health, Ministry of Public Health, Tivanon Road, Muang, Nonthaburi, Thailand.

出版信息

Drug Alcohol Rev. 2010 Jul;29(4):456-61. doi: 10.1111/j.1465-3362.2010.00196.x.

DOI:10.1111/j.1465-3362.2010.00196.x

PMID:20636664

Abstract

INTRODUCTION AND AIMS

As a consequence of the methamphetamine epidemic in Thailand, the occurrence of methamphetamine psychosis (MAP) dramatically increased. This study aimed to examine the long-term outcomes of MAP patients following their first presentation to a psychiatric hospital.

DESIGN AND METHODS

Methamphetamine psychosis patients who were first hospitalised in Suan Prung psychiatric hospital Thailand in 2000-2001 were identified through a review of the hospital database. Eligible participants were scheduled for visits by trained field researchers in 2007. For those giving consent, a structured face-to-face interview was conducted. Outcomes were collected from both medical records and interviews.

RESULTS

A total of 1116 participants were included in the study. Ninety-two (8.2%) participants had died from suicide, accident or AIDS. Due to relocation, only 449 (40.2%) individuals were interviewed. Most of the participants were male (90.6%) with a mean age of 33.3 years (SD = 8.0). The medical records showed that 263 had revisited the hospital in the interim. Of those, 39.2% were re-hospitalised and 38% were given a diagnosis of schizophrenia due to persistent psychosis. The outreach interview found that more than half (55.7%) had experienced psychosis relapse. Mini International Neuropsychiatric Interview revealed the following current conditions: psychotic disorders (15.8%), alcohol use disorders (52.1%) and suicidality (22.3%). Participants who did not have a diagnosis of current methamphetamine abuse could be divided into those with a single episode psychosis (52.6%) and those with chronic course of psychosis (38.8%).

DISCUSSION AND CONCLUSIONS

Individuals with MAP are likely to have poor outcomes, in terms of premature death, several relapses of psychotic symptoms, chronic psychotic manifestation, and very rates of alcohol use disorder and suicidality. Therefore, those individuals with MAP require long-term monitoring and psychiatric care.

摘要

引言和目的

由于泰国冰毒泛滥，导致出现了大量的冰毒精神病（MAP）患者。本研究旨在观察首次入住泰国顺蓬精神病院的 MAP 患者的长期预后。

设计与方法

通过对医院数据库的审查，确定了 2000-2001 年在顺蓬精神病院首次住院的冰毒精神病患者。符合条件的患者在 2007 年接受了经过培训的现场研究人员的随访。对于同意参加的患者，进行了结构化的面对面访谈。通过病历和访谈收集结局数据。

结果

本研究共纳入 1116 名参与者。92 名（8.2%）患者因自杀、意外或艾滋病而死亡。由于搬迁，只有 449 名（40.2%）患者接受了访谈。大多数参与者为男性（90.6%），平均年龄为 33.3 岁（标准差=8.0）。病历显示，在此期间有 263 名患者再次住院。其中，39.2%的患者再次住院，38%的患者因持续精神病而被诊断为精神分裂症。外展访谈发现，超过一半（55.7%）的患者出现了精神病复发。迷你国际神经精神访谈显示，目前的状况如下：精神病障碍（15.8%）、酒精使用障碍（52.1%）和自杀意念（22.3%）。没有当前冰毒滥用诊断的患者可以分为单次精神病发作（52.6%）和慢性精神病发作（38.8%）。