Division of Thoracic Surgery, Department of Surgery, The University of Western Ontario, London, Ontario, Canada.
J Thorac Cardiovasc Surg. 2010 Dec;140(6):1272-5. doi: 10.1016/j.jtcvs.2010.06.026. Epub 2010 Jul 16.
We measured lung function before and after video-assisted thoracoscopic apical bullectomy and talc poudrage in patients with spontaneous pneumothoraces.
Seventy-two patients were prospectively followed up for 12 months. The indications for surgery were recurrent pneumothoraces (n = 58), bilateral pneumothoraces (n = 8), and persistent air leak (n = 6). There were 46 males and 26 females with mean age of 29 years (range 15-61 years). The results were analyzed using paired t tests.
There were no recurrences. There were 4 complications (5.6%): 1 wound infection, 1 case of pneumonia, and 2 persistent air leaks each lasting 1 week. There were no conversions to open surgery. Preoperative and 6-month pulmonary function test results were available on 41 patients, and 35 patients completed 12-month pulmonary function tests. Twelve-month values (mean percent ± SD) were as follows: Forced expiratory volume in 1 second fell from 95 ± 19 to 89 ± 16 (P = .02); forced expiratory volume in 1 second/forced vital capacity ratio was unchanged, 95 ± 12 versus 94 ± 13 (P = .9); total lung capacity fell from 106 ± 19 to 98 ± 12 (P = 0.002); vital capacity fell from 100 ± 22 to 96 ± 16 (P = .05); residual volume fell from 126 ± 32 to 107 ± 29 (P = .002); and diffusion capacity for carbon monoxide corrected for alveolar volume was unchanged, 88 ± 15 versus 91 ± 17 (P = .07). Flow rates and diffusion capacities were preserved, but lung volumes were slightly reduced at 1 year.
Video-assisted thoracoscopic apical bullectomy and talc poudrage is an effective treatment for spontaneous pneumothoraces with a low complication rate and recurrence rate and only minor changes in pulmonary function at 1 year.
我们测量了自发性气胸患者行电视辅助胸腔镜下尖部肺大疱切除术和滑石粉喷洒术后的肺功能。
72 例患者前瞻性随访 12 个月。手术适应证为复发性气胸(n=58)、双侧气胸(n=8)和持续性漏气(n=6)。男性 46 例,女性 26 例,平均年龄 29 岁(15-61 岁)。采用配对 t 检验进行分析。
无复发。有 4 例并发症(5.6%):1 例伤口感染,1 例肺炎,2 例持续漏气,各持续 1 周。无中转开胸手术。41 例患者术前和 6 个月的肺功能检查结果可用,35 例患者完成 12 个月的肺功能检查。12 个月时的数值(均值±标准差)如下:用力呼气量从 95±19 降至 89±16(P=0.02);用力呼气量/用力肺活量比值无变化,分别为 95±12 和 94±13(P=0.9);总肺容量从 106±19 降至 98±12(P=0.002);肺活量从 100±22 降至 96±16(P=0.05);残气量从 126±32 降至 107±29(P=0.002);一氧化碳弥散量校正肺泡容积无变化,分别为 88±15 和 91±17(P=0.07)。流量和弥散量保持不变,但肺容积在 1 年内略有减少。
电视辅助胸腔镜下尖部肺大疱切除术和滑石粉喷洒术是治疗自发性气胸的有效方法,并发症和复发率低,1 年后肺功能仅有轻微变化。